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STRINGSTRING
ENSG00000258941 ENSG00000258941 MIA2 MIA2 CTAGE5 CTAGE5 USP17L2 USP17L2 USP17L7 USP17L7 USP17L24 USP17L24 DEFB108B DEFB108B DEFB104A DEFB104A DEFB104B DEFB104B DEFB107B DEFB107B DEFB107A DEFB107A
"USP17L7" - Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP17L7Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7; Ubiquitin specific peptidase 17-like family member 7 (530 aa)    
Predicted Functional Partners:
USP17L2
Ubiquitin carboxyl-terminal hydrolase 17; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Regulates cell proliferation by deubiquitinating and inhibiting RCE1 thereby controlling the small GTPases NRAS and HRAS localization and activation. In parallel, mediates deubiquitination of CDC25A, preventing CDC25A degradation by the proteasome during the G1/S and G2/M phases promoting cell-cycle progression. Also regulates cell proliferation and apoptosis through deubiquitination of SUDS3 a regulator of histone deacetyl [...] (530 aa)
      
 
0.674
DEFB108B
Beta-defensin 108B; Has antibacterial activity; Defensins, beta (73 aa)
            
  0.589
DEFB107A
Defensin, beta 107A; Has antibacterial activity; Defensins, beta (70 aa)
            
  0.582
DEFB107B
Beta-defensin 107; Has antibacterial activity; Defensins, beta (70 aa)
            
  0.571
ENSG00000258941
Endoplasmic reticulum export factor CTAGE5; cTAGE family member 5 (1339 aa)
            
  0.556
USP17L24
Ubiquitin specific peptidase 17-like family member 24; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection (530 aa)
        
   
0.552
DEFB104B
Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family (72 aa)
            
  0.534
MIA2
Endoplasmic reticulum export factor CTAGE5; Melanoma inhibitory activity 2; MIA family (654 aa)
            
  0.534
DEFB104A
Defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Defensins, beta (72 aa)
            
  0.533
CTAGE5
Endoplasmic reticulum export factor CTAGE5; Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites; CTAGE family (809 aa)
            
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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