• Version:
  • 11.0 [archived version]
STRINGSTRING
MKRN3 MKRN3 ENSG00000242631 ENSG00000242631 OR10S1 OR10S1 DCLRE1B DCLRE1B ZNF283 ZNF283 LCE2C LCE2C KRT6C KRT6C SNX32 SNX32 CTSW CTSW
"ZNF283" - Zinc finger protein 283 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
ZNF283Zinc finger protein 283; May be involved in transcriptional regulation; Zinc fingers C2H2-type (679 aa)    
Predicted Functional Partners:
SNX32
Sorting nexin-32; May be involved in several stages of intracellular trafficking; PX-BAR domain containing (403 aa)
           
  0.550
KRT6C
Keratin, type II cytoskeletal 6C; Keratins, type II; Belongs to the intermediate filament family (564 aa)
           
  0.471
MKRN3
Probable E3 ubiquitin-protein ligase makorin-3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Ring finger proteins (507 aa)
           
  0.453
ENSG00000242631
Zinc finger protein 462 (87 aa)
           
  0.447
CTSW
Cathepsin W; May have a specific function in the mechanism or regulation of T-cell cytolytic activity; Cathepsins (376 aa)
     
 
  0.444
OR10S1
Olfactory receptor 10S1; Odorant receptor; Olfactory receptors, family 10 (331 aa)
           
  0.428
LCE2C
Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum (110 aa)
           
  0.420
DCLRE1B
5’ exonuclease Apollo; 5’-3’ exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)- mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity- generates 3’ single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres [...] (532 aa)
     
   
  0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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