| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BFSP1 | CHMP4B | ENSP00000367104 | ENSP00000217402 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | 0.728 |
| BFSP1 | CRYBA4 | ENSP00000367104 | ENSP00000346805 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Beta-crystallin A4; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.716 |
| BFSP1 | CRYBB1 | ENSP00000367104 | ENSP00000215939 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Beta-crystallin B1; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.750 |
| BFSP1 | CRYBB2 | ENSP00000367104 | ENSP00000381273 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Beta-crystallin B2; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.707 |
| BFSP1 | CRYBB3 | ENSP00000367104 | ENSP00000215855 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Beta-crystallin B3; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.740 |
| BFSP1 | CRYGD | ENSP00000367104 | ENSP00000264376 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Gamma-crystallin D; Crystallins are the dominant structural components of the vertebrate eye lens | 0.689 |
| BFSP1 | GJA3 | ENSP00000367104 | ENSP00000241125 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Gap junction alpha-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Alpha-type (group II) subfamily | 0.725 |
| BFSP1 | LIM2 | ENSP00000367104 | ENSP00000221973 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Lens intrinsic membrane protein 2 | 0.740 |
| BFSP1 | TMEM114 | ENSP00000367104 | ENSP00000484263 | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | Transmembrane protein 114 | 0.734 |
| CHMP4B | BFSP1 | ENSP00000217402 | ENSP00000367104 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | 0.728 |
| CHMP4B | CRYBA4 | ENSP00000217402 | ENSP00000346805 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Beta-crystallin A4; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.699 |
| CHMP4B | CRYBB1 | ENSP00000217402 | ENSP00000215939 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Beta-crystallin B1; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.698 |
| CHMP4B | CRYBB2 | ENSP00000217402 | ENSP00000381273 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Beta-crystallin B2; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.694 |
| CHMP4B | CRYBB3 | ENSP00000217402 | ENSP00000215855 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Beta-crystallin B3; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | 0.667 |
| CHMP4B | CRYGD | ENSP00000217402 | ENSP00000264376 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Gamma-crystallin D; Crystallins are the dominant structural components of the vertebrate eye lens | 0.641 |
| CHMP4B | GJA3 | ENSP00000217402 | ENSP00000241125 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Gap junction alpha-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Alpha-type (group II) subfamily | 0.685 |
| CHMP4B | LIM2 | ENSP00000217402 | ENSP00000221973 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Lens intrinsic membrane protein 2 | 0.698 |
| CHMP4B | TMEM114 | ENSP00000217402 | ENSP00000484263 | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | Transmembrane protein 114 | 0.777 |
| CRYBA4 | BFSP1 | ENSP00000346805 | ENSP00000367104 | Beta-crystallin A4; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | Filensin; Beaded filament structural protein 1; Belongs to the intermediate filament family | 0.716 |
| CRYBA4 | CHMP4B | ENSP00000346805 | ENSP00000217402 | Beta-crystallin A4; Crystallins are the dominant structural components of the vertebrate eye lens; Belongs to the beta/gamma-crystallin family | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...] | 0.699 |
