node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf53 | COLCA2 | ENSP00000280325 | ENSP00000484135 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | Colorectal cancer associated 2 | 0.900 |
C11orf53 | DIP2B | ENSP00000280325 | ENSP00000301180 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | Disco interacting protein 2 homolog B | 0.637 |
C11orf53 | EIF3H | ENSP00000280325 | ENSP00000429931 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.418 |
C11orf53 | FAM186A | ENSP00000280325 | ENSP00000329995 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family | 0.532 |
C11orf53 | POU2AF1 | ENSP00000280325 | ENSP00000376786 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | POU domain class 2-associating factor 1; Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers; Belongs to the POU2AF1 family | 0.571 |
C11orf53 | SHROOM2 | ENSP00000280325 | ENSP00000370299 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity); Belongs to the shroom family | 0.526 |
COLCA2 | C11orf53 | ENSP00000484135 | ENSP00000280325 | Colorectal cancer associated 2 | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | 0.900 |
COLCA2 | DIP2B | ENSP00000484135 | ENSP00000301180 | Colorectal cancer associated 2 | Disco interacting protein 2 homolog B | 0.630 |
COLCA2 | EIF3H | ENSP00000484135 | ENSP00000429931 | Colorectal cancer associated 2 | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.539 |
COLCA2 | FAM186A | ENSP00000484135 | ENSP00000329995 | Colorectal cancer associated 2 | Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family | 0.530 |
COLCA2 | HIGD1A | ENSP00000484135 | ENSP00000398064 | Colorectal cancer associated 2 | HIG1 domain family member 1A, mitochondrial; Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes | 0.721 |
COLCA2 | NXPE1 | ENSP00000484135 | ENSP00000251921 | Colorectal cancer associated 2 | NXPE family member 1; Neurexophilin and PC-esterase domain family member 1; Belongs to the NXPE family | 0.559 |
COLCA2 | POU2AF1 | ENSP00000484135 | ENSP00000376786 | Colorectal cancer associated 2 | POU domain class 2-associating factor 1; Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers; Belongs to the POU2AF1 family | 0.478 |
COLCA2 | POU3F1 | ENSP00000484135 | ENSP00000362103 | Colorectal cancer associated 2 | POU domain, class 3, transcription factor 1; Transcription factor that binds to the octamer motif (5’-ATTTGCAT-3’). Thought to be involved in early embryogenesis and neurogenesis; POU class homeoboxes and pseudogenes | 0.575 |
COLCA2 | SHROOM2 | ENSP00000484135 | ENSP00000370299 | Colorectal cancer associated 2 | Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity); Belongs to the shroom family | 0.518 |
COLCA2 | WBP1L | ENSP00000484135 | ENSP00000414721 | Colorectal cancer associated 2 | WW domain binding protein 1 like; WBP1/VOPP1 family | 0.717 |
DIP2B | C11orf53 | ENSP00000301180 | ENSP00000280325 | Disco interacting protein 2 homolog B | Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53 | 0.637 |
DIP2B | COLCA2 | ENSP00000301180 | ENSP00000484135 | Disco interacting protein 2 homolog B | Colorectal cancer associated 2 | 0.630 |
DIP2B | FAM186A | ENSP00000301180 | ENSP00000329995 | Disco interacting protein 2 homolog B | Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family | 0.543 |
DIP2B | SHROOM2 | ENSP00000301180 | ENSP00000370299 | Disco interacting protein 2 homolog B | Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity); Belongs to the shroom family | 0.445 |