• Version:
  • 11.0 [archived version]
STRINGSTRING
C20orf195 C20orf195 ERV3-1 ERV3-1 SIN3B SIN3B SH3RF3 SH3RF3 ZNF107 ZNF107 C1orf174 C1orf174 KIAA2026 KIAA2026 LUC7L3 LUC7L3 HAGHL HAGHL CSRNP2 CSRNP2 ZNF207 ZNF207
"ZNF107" - Zinc finger protein 107 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF107Zinc finger protein 107; May be involved in transcriptional regulation; Zinc fingers C2H2-type (852 aa)    
Predicted Functional Partners:
C1orf174
UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family (243 aa)
           
  0.510
HAGHL
Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds (282 aa)
           
  0.472
SH3RF3
SH3 domain containing ring finger 3 (882 aa)
     
 
  0.451
C20orf195
Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195 (318 aa)
           
  0.441
ZNF207
BUB3-interacting and GLEBS motif-containing protein ZNF207; Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetoc [...] (494 aa)
           
  0.431
ERV3-1
Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes (604 aa)
           
  0.420
KIAA2026
Uncharacterized protein KIAA2026; KIAA2026 (2103 aa)
           
  0.420
CSRNP2
Cysteine/serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis; Protein phosphatase 1 regulatory subunits (543 aa)
           
  0.420
LUC7L3
Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family (432 aa)
     
   
  0.411
SIN3B
Paired amphipathic helix protein Sin3b; Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression (1162 aa)
     
 
  0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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