node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEACAM8 | GOLGA6L22 | ENSP00000244336 | ENSP00000483673 | Carcinoembryonic antigen related cell adhesion molecule family; Belongs to the immunoglobulin superfamily. CEA family | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | 0.426 |
DHX16 | GOLGA6L22 | ENSP00000365625 | ENSP00000483673 | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | 0.522 |
GOLGA6L22 | CEACAM8 | ENSP00000483673 | ENSP00000244336 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Carcinoembryonic antigen related cell adhesion molecule family; Belongs to the immunoglobulin superfamily. CEA family | 0.426 |
GOLGA6L22 | DHX16 | ENSP00000483673 | ENSP00000365625 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily | 0.522 |
GOLGA6L22 | GOLGB1 | ENSP00000483673 | ENSP00000377275 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | 0.416 |
GOLGA6L22 | GOSR1 | ENSP00000483673 | ENSP00000225724 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.425 |
GOLGA6L22 | MUL1 | ENSP00000483673 | ENSP00000264198 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Mitochondrial ubiquitin ligase activator of NFKB 1; Exhibits weak E3 ubiquitin-protein ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Can ubiquitinate AKT1 preferentially at ’Lys-284’ involving ’Lys-48’-linked polyubiquitination and seems to be involved in regulation of Akt signaling by targeting phosphorylated Akt to proteosomal degradation. Proposed to preferentially act as a SUMO E3 ligase at physiological concentrations. Plays a role in the con [...] | 0.441 |
GOLGA6L22 | PRR5 | ENSP00000483673 | ENSP00000384848 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Proline-rich protein 5; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 ’Ser-473’ phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT [...] | 0.440 |
GOLGA6L22 | RNF13 | ENSP00000483673 | ENSP00000341361 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation; Ring finger proteins | 0.581 |
GOLGA6L22 | STX5 | ENSP00000483673 | ENSP00000294179 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus; Syntaxins | 0.425 |
GOLGA6L22 | USO1 | ENSP00000483673 | ENSP00000444850 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity; Armadillo-like helical domain containing | 0.423 |
GOLGA6L22 | YIF1A | ENSP00000483673 | ENSP00000366098 | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family | 0.407 |
GOLGB1 | GOLGA6L22 | ENSP00000377275 | ENSP00000483673 | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | 0.416 |
GOLGB1 | GOSR1 | ENSP00000377275 | ENSP00000225724 | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.988 |
GOLGB1 | STX5 | ENSP00000377275 | ENSP00000294179 | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus; Syntaxins | 0.987 |
GOLGB1 | USO1 | ENSP00000377275 | ENSP00000444850 | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity; Armadillo-like helical domain containing | 0.994 |
GOSR1 | GOLGA6L22 | ENSP00000225724 | ENSP00000483673 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | Golgin subfamily A member 6-like protein 22 ; Belongs to the GOLGA6 family | 0.425 |
GOSR1 | GOLGB1 | ENSP00000225724 | ENSP00000377275 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | Golgin subfamily B member 1; May participate in forming intercisternal cross-bridges of the Golgi complex | 0.988 |
GOSR1 | STX5 | ENSP00000225724 | ENSP00000294179 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus; Syntaxins | 0.999 |
GOSR1 | USO1 | ENSP00000225724 | ENSP00000444850 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity; Armadillo-like helical domain containing | 0.992 |