node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EVX2 | SKOR2 | ENSP00000312385 | ENSP00000483333 | Homeobox even-skipped homolog protein 2; HOXL subclass homeoboxes; Belongs to the even-skipped homeobox family | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.606 |
HDHD2 | NOC3L | ENSP00000300605 | ENSP00000360412 | Haloacid dehalogenase like hydrolase domain containing 2 | Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing | 0.654 |
HDHD2 | SKOR2 | ENSP00000300605 | ENSP00000483333 | Haloacid dehalogenase like hydrolase domain containing 2 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.703 |
HDHD2 | TBC1D12 | ENSP00000300605 | ENSP00000225235 | Haloacid dehalogenase like hydrolase domain containing 2 | TBC1 domain family member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.682 |
IRX1 | SKOR2 | ENSP00000305244 | ENSP00000483333 | Iroquois-class homeodomain protein IRX-1; TALE class homeoboxes and pseudogenes | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.543 |
IRX1 | SLC5A8 | ENSP00000305244 | ENSP00000445340 | Iroquois-class homeodomain protein IRX-1; TALE class homeoboxes and pseudogenes | Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D- hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+)-substrate stoichiometry of between 4-1 and 2-1. Catalyzes passive carrier mediated diffusion of iodide. Med [...] | 0.427 |
KIRREL2 | SKOR2 | ENSP00000353331 | ENSP00000483333 | Kin of IRRE-like protein 2; Kirre like nephrin family adhesion molecule 2; C2-set domain containing | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.589 |
NOC3L | HDHD2 | ENSP00000360412 | ENSP00000300605 | Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing | Haloacid dehalogenase like hydrolase domain containing 2 | 0.654 |
NOC3L | SKOR2 | ENSP00000360412 | ENSP00000483333 | Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.539 |
NOC3L | TBC1D12 | ENSP00000360412 | ENSP00000225235 | Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing | TBC1 domain family member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.523 |
SEPT9 | SKOR2 | ENSP00000391249 | ENSP00000483333 | Septin-9; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | 0.556 |
SEPT9 | SLC5A8 | ENSP00000391249 | ENSP00000445340 | Septin-9; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D- hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+)-substrate stoichiometry of between 4-1 and 2-1. Catalyzes passive carrier mediated diffusion of iodide. Med [...] | 0.443 |
SKOR2 | EVX2 | ENSP00000483333 | ENSP00000312385 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Homeobox even-skipped homolog protein 2; HOXL subclass homeoboxes; Belongs to the even-skipped homeobox family | 0.606 |
SKOR2 | HDHD2 | ENSP00000483333 | ENSP00000300605 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Haloacid dehalogenase like hydrolase domain containing 2 | 0.703 |
SKOR2 | IRX1 | ENSP00000483333 | ENSP00000305244 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Iroquois-class homeodomain protein IRX-1; TALE class homeoboxes and pseudogenes | 0.543 |
SKOR2 | KIRREL2 | ENSP00000483333 | ENSP00000353331 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Kin of IRRE-like protein 2; Kirre like nephrin family adhesion molecule 2; C2-set domain containing | 0.589 |
SKOR2 | NOC3L | ENSP00000483333 | ENSP00000360412 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Nucleolar complex protein 3 homolog; May be required for adipogenesis; Armadillo-like helical domain containing | 0.539 |
SKOR2 | SEPT9 | ENSP00000483333 | ENSP00000391249 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Septin-9; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | 0.556 |
SKOR2 | SLC5A8 | ENSP00000483333 | ENSP00000445340 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D- hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+)-substrate stoichiometry of between 4-1 and 2-1. Catalyzes passive carrier mediated diffusion of iodide. Med [...] | 0.582 |
SKOR2 | SMAD2 | ENSP00000483333 | ENSP00000262160 | SKI family transcriptional corepressor 2; Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system; SKI transcriptional corepressors | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator | 0.668 |