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STRINGSTRING
FAM83D FAM83D GOLGA8M GOLGA8M HMMR HMMR POTEC POTEC GOLGA8S GOLGA8S 339010 339010 POTED POTED TRIM23 TRIM23 GOLGA8K GOLGA8K POTEB2 POTEB2 GOLGA6L1 GOLGA6L1
"339010" - Homo sapiens POTE ankyrin domain family, member B-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
339010Homo sapiens POTE ankyrin domain family, member B-like (LOC102724631), transcript variant 1, mRNA; Belongs to the POTE family (581 aa)    
Predicted Functional Partners:
POTED
POTE ankyrin domain family member D; Belongs to the POTE family (584 aa)
        
 
0.821
POTEC
POTE ankyrin domain family member C (542 aa)
        
   
0.815
GOLGA8M
Golgin A8 family member M (632 aa)
        
 
  0.718
GOLGA8S
Golgin A8 family member S (625 aa)
        
 
  0.713
GOLGA8K
Golgin A8 family member K; Belongs to the GOLGA8 family (630 aa)
        
 
  0.710
TRIM23
E3 ubiquitin-protein ligase TRIM23; Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in ’Lys-63’-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit; In the C-terminal section; belongs to the small GTPase superfamily. Arf family (574 aa)
        
 
  0.692
FAM83D
Protein FAM83D; Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 (615 aa)
        
      0.607
GOLGA6L1
Golgin subfamily A member 6-like protein 1; Golgin A6 family-like 1; Belongs to the GOLGA6 family (668 aa)
        
 
  0.559
POTEB2
POTE ankyrin domain family member B2; Belongs to the POTE family (544 aa)
        
   
0.558
HMMR
Hyaluronan mediated motility receptor; Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity); CD molecules (725 aa)
        
      0.550
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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