node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DGCR2 | DGCR6L | ENSP00000263196 | ENSP00000248879 | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | Protein DGCR6L; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | 0.641 |
DGCR2 | ENSG00000183628 | ENSP00000263196 | ENSP00000331681 | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | 0.641 |
DGCR2 | ENSG00000183628 | ENSP00000263196 | ENSP00000482514 | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | Protein DGCR6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | 0.641 |
DGCR2 | ZNF74 | ENSP00000263196 | ENSP00000483077 | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.630 |
DGCR6L | DGCR2 | ENSP00000248879 | ENSP00000263196 | Protein DGCR6L; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | 0.641 |
DGCR6L | ZNF74 | ENSP00000248879 | ENSP00000483077 | Protein DGCR6L; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.641 |
ENSG00000183628 | DGCR2 | ENSP00000482514 | ENSP00000263196 | Protein DGCR6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | 0.641 |
ENSG00000183628 | DGCR2 | ENSP00000331681 | ENSP00000263196 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Integral membrane protein DGCR2/IDD; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration; C-type lectin domain containing | 0.641 |
ENSG00000183628 | ZNF74 | ENSP00000331681 | ENSP00000483077 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.641 |
ENSG00000183628 | ZNF74 | ENSP00000482514 | ENSP00000483077 | Protein DGCR6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches; Belongs to the gonadal family | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.641 |
LZTR1 | MED15 | ENSP00000215739 | ENSP00000263205 | Leucine-zipper-like transcriptional regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis; BTB domain containing | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol- [...] | 0.522 |
LZTR1 | SCARF2 | ENSP00000215739 | ENSP00000477564 | Leucine-zipper-like transcriptional regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis; BTB domain containing | Scavenger receptor class F member 2; Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity); Scavenger receptors | 0.470 |
LZTR1 | ZNF74 | ENSP00000215739 | ENSP00000483077 | Leucine-zipper-like transcriptional regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis; BTB domain containing | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.651 |
MED15 | LZTR1 | ENSP00000263205 | ENSP00000215739 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol- [...] | Leucine-zipper-like transcriptional regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis; BTB domain containing | 0.522 |
MED15 | ZNF74 | ENSP00000263205 | ENSP00000483077 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol- [...] | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.644 |
SCARF2 | LZTR1 | ENSP00000477564 | ENSP00000215739 | Scavenger receptor class F member 2; Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity); Scavenger receptors | Leucine-zipper-like transcriptional regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis; BTB domain containing | 0.470 |
SCARF2 | ZNF74 | ENSP00000477564 | ENSP00000483077 | Scavenger receptor class F member 2; Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity); Scavenger receptors | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.638 |
TATDN1 | ZNF74 | ENSP00000276692 | ENSP00000483077 | Putative deoxyribonuclease TATDN1; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.700 |
TRIM28 | ZNF74 | ENSP00000253024 | ENSP00000483077 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.944 |
ZNF69 | ZNF74 | ENSP00000345333 | ENSP00000483077 | Zinc finger protein 69; Zinc fingers C2H2-type | Zinc finger protein 74; May play a role in RNA metabolism; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.800 |