• Version:
  • 11.0 [archived version]
STRINGSTRING
C12orf5 C12orf5 LRRC75A LRRC75A TRIM73 TRIM73 BBOX1 BBOX1 TRIM52 TRIM52 SPANXN3 SPANXN3 TRAT1 TRAT1 TRIML2 TRIML2 TRIM2 TRIM2 TMLHE TMLHE CMYA5 CMYA5
"TRIM52" - Tripartite motif containing 52 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TRIM52Tripartite motif containing 52; Ring finger proteins (297 aa)    
Predicted Functional Partners:
TRIML2
Probable E3 ubiquitin-protein ligase TRIML2; Tripartite motif family like 2 (387 aa)
           
  0.765
LRRC75A
Leucine-rich repeat-containing protein 75A; Leucine rich repeat containing 75A (344 aa)
           
  0.693
CMYA5
Cardiomyopathy-associated protein 5; May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A (By similarity). May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration (By similarity); A-kinase anchoring proteins (4069 aa)
           
  0.649
TRIM2
Tripartite motif-containing protein 2; UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance; Belongs to the TRIM/RBCC family (771 aa)
           
  0.528
TMLHE
Trimethyllysine dioxygenase, mitochondrial; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML); Belongs to the gamma-BBH/TMLD family (421 aa)
           
  0.518
BBOX1
Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family (387 aa)
           
  0.510
C12orf5
Fructose-2,6-bisphosphatase TIGAR; Fructose-bisphosphatase hydrolyzing fructose-2,6- bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death. Plays a [...] (270 aa)
     
   
  0.499
SPANXN3
Sperm protein associated with the nucleus on the X chromosome N3; SPANX family member N3; Belongs to the SPAN-X family (141 aa)
           
  0.493
TRIM73
Tripartite motif containing 73; Belongs to the TRIM/RBCC family (250 aa)
     
   
  0.488
TRAT1
T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells (186 aa)
           
  0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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