• Version:
  • 11.0 [archived version]
STRINGSTRING
TMC3 TMC3 OR4F15 OR4F15 C14orf6 C14orf6 C19orf52 C19orf52 FAM45A FAM45A ZNF343 ZNF343 TRIM28 TRIM28 ENSG00000259060 ENSG00000259060 C3orf52 C3orf52 CLVS2 CLVS2 SLC22A24 SLC22A24
"ZNF343" - Zinc finger protein 343 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF343Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (640 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
OR4F15
Olfactory receptor 4F15; Odorant receptor; Olfactory receptors, family 4 (312 aa)
           
  0.709
TMC3
Transmembrane channel-like protein 3; Probable ion channel; Transmembrane channel likes (1100 aa)
           
  0.669
CLVS2
Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (327 aa)
     
 
  0.595
FAM45A
Protein FAM45A; Family with sequence similarity 45 member A (357 aa)
           
  0.570
C3orf52
TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 (250 aa)
           
  0.530
ENSG00000259060
Ribonuclease A family member 11 (199 aa)
           
  0.512
C14orf6
Ribonuclease, RNase A family, 11 (non-active); Ribonuclease A family member 11 (199 aa)
           
  0.512
C19orf52
Mitochondrial import inner membrane translocase subunit Tim29; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as the external driving force. Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex. May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40 (260 aa)
           
  0.511
SLC22A24
Solute carrier family 22 member 24 (552 aa)
           
  0.491
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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