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  • 11.0 [archived version]
STRINGSTRING
C17orf62 C17orf62 ZAK ZAK RFPL3S RFPL3S ANKMY1 ANKMY1 TRIM28 TRIM28 ZNF227 ZNF227 RIMBP2 RIMBP2 TMEM132C TMEM132C LRRIQ1 LRRIQ1 FAM174B FAM174B FAM129C FAM129C
"ZNF227" - Zinc finger protein 227 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ZNF227Zinc finger protein 227; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (799 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
      
    0.903
ZAK
Mitogen-activated protein kinase kinase kinase 20; Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Involved in limb development (800 aa)
      
      0.513
ANKMY1
Ankyrin repeat and MYND domain containing 1 (1030 aa)
            
  0.474
C17orf62
Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 (187 aa)
            
  0.473
FAM174B
Membrane protein FAM174B; Family with sequence similarity 174 member B (159 aa)
            
  0.473
LRRIQ1
Leucine rich repeats and IQ motif containing 1 (1722 aa)
        
 
  0.454
FAM129C
Niban-like protein 2; Family with sequence similarity 129 member C; Belongs to the Niban family (697 aa)
            
  0.443
RFPL3S
Putative protein RFPL3S; RFPL3 antisense (107 aa)
            
  0.430
TMEM132C
Transmembrane protein 132C; Protein phosphatase 1 regulatory subunits (1108 aa)
            
  0.430
RIMBP2
RIMS-binding protein 2; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B; Protein phosphatase 1 regulatory subunits (1052 aa)
            
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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