• Version:
  • 11.0 [archived version]
STRINGSTRING
PRPSAP1 PRPSAP1 FAM173A FAM173A METTL10 METTL10 MXRA7 MXRA7 FAM86A FAM86A METTL23 METTL23 METTL20 METTL20 JMJD6 JMJD6 METTL18 METTL18 METTL22 METTL22 N6AMT2 N6AMT2
"METTL23" - Methyltransferase-like protein 23 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL23Methyltransferase-like protein 23; Probable methyltransferase (190 aa)    
Predicted Functional Partners:
MXRA7
Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 (204 aa)
           
  0.801
METTL18
Histidine protein methyltransferase 1 homolog; Probable histidine methyltransferase (372 aa)
     
   
  0.754
FAM86A
Protein-lysine N-methyltransferase EEF2KMT; Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on ’Lys-525’ (330 aa)
       
 
  0.747
METTL22
Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN; Belongs to the methyltransferase superfamily. METTL22 family (404 aa)
       
 
  0.747
METTL20
Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain (262 aa)
     
   
  0.704
PRPSAP1
Phosphoribosyl pyrophosphate synthase-associated protein 1; Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis (385 aa)
           
  0.642
N6AMT2
EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’ (214 aa)
           
  0.604
METTL10
EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ (291 aa)
     
   
  0.599
FAM173A
Protein FAM173A; Seven-beta-strand methyltransferase motif containing (235 aa)
           
  0.588
JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an argi [...] (414 aa)
     
   
  0.570
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]