node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCBL2 | CDRT4 | ENSP00000260508 | ENSP00000482523 | Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By s [...] | CMT1A duplicated region transcript 4 | 0.530 |
CCBL2 | LRRC9 | ENSP00000260508 | ENSP00000454748 | Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By s [...] | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | 0.496 |
CDRT4 | CCBL2 | ENSP00000482523 | ENSP00000260508 | CMT1A duplicated region transcript 4 | Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By s [...] | 0.530 |
CDRT4 | FOCAD | ENSP00000482523 | ENSP00000369599 | CMT1A duplicated region transcript 4 | Focadhesin; Potential tumor suppressor in gliomas; Armadillo-like helical domain containing | 0.531 |
CDRT4 | ITFG1 | ENSP00000482523 | ENSP00000319918 | CMT1A duplicated region transcript 4 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.532 |
CDRT4 | LRRC9 | ENSP00000482523 | ENSP00000454748 | CMT1A duplicated region transcript 4 | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | 0.669 |
CDRT4 | RHBDD1 | ENSP00000482523 | ENSP00000375914 | CMT1A duplicated region transcript 4 | Rhomboid-related protein 4; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfe [...] | 0.542 |
CDRT4 | SNTG1 | ENSP00000482523 | ENSP00000429842 | CMT1A duplicated region transcript 4 | Gamma-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation; Belongs to the syntrophin family | 0.473 |
CDRT4 | TEKT3 | ENSP00000482523 | ENSP00000379263 | CMT1A duplicated region transcript 4 | Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins | 0.596 |
CDRT4 | TVP23B | ENSP00000482523 | ENSP00000305654 | CMT1A duplicated region transcript 4 | Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family | 0.456 |
CDRT4 | TVP23C | ENSP00000482523 | ENSP00000225576 | CMT1A duplicated region transcript 4 | Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family | 0.783 |
CDRT4 | ZNF287 | ENSP00000482523 | ENSP00000379168 | CMT1A duplicated region transcript 4 | Zinc finger protein 287; May be involved in transcriptional regulation; SCAN domain containing | 0.533 |
FOCAD | CDRT4 | ENSP00000369599 | ENSP00000482523 | Focadhesin; Potential tumor suppressor in gliomas; Armadillo-like helical domain containing | CMT1A duplicated region transcript 4 | 0.531 |
FOCAD | LRRC9 | ENSP00000369599 | ENSP00000454748 | Focadhesin; Potential tumor suppressor in gliomas; Armadillo-like helical domain containing | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | 0.473 |
ITFG1 | CDRT4 | ENSP00000319918 | ENSP00000482523 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | CMT1A duplicated region transcript 4 | 0.532 |
ITFG1 | TVP23C | ENSP00000319918 | ENSP00000225576 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family | 0.450 |
LRRC9 | CCBL2 | ENSP00000454748 | ENSP00000260508 | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By s [...] | 0.496 |
LRRC9 | CDRT4 | ENSP00000454748 | ENSP00000482523 | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | CMT1A duplicated region transcript 4 | 0.669 |
LRRC9 | FOCAD | ENSP00000454748 | ENSP00000369599 | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | Focadhesin; Potential tumor suppressor in gliomas; Armadillo-like helical domain containing | 0.473 |
LRRC9 | RHBDD1 | ENSP00000454748 | ENSP00000375914 | Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 | Rhomboid-related protein 4; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfe [...] | 0.473 |