• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF287 ZNF287 FOCAD FOCAD TEKT3 TEKT3 RHBDD1 RHBDD1 TVP23B TVP23B CDRT4 CDRT4 LRRC9 LRRC9 CCBL2 CCBL2 ITFG1 ITFG1 SNTG1 SNTG1 TVP23C TVP23C
"CDRT4" - CMT1A duplicated region transcript 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
CDRT4CMT1A duplicated region transcript 4 (152 aa)    
Predicted Functional Partners:
TVP23C
Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family (276 aa)
     
   
  0.783
LRRC9
Leucine-rich repeat-containing protein 9; Leucine rich repeat containing 9 (1453 aa)
           
  0.669
TEKT3
Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins (490 aa)
     
   
  0.596
RHBDD1
Rhomboid-related protein 4; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfe [...] (315 aa)
           
  0.542
ZNF287
Zinc finger protein 287; May be involved in transcriptional regulation; SCAN domain containing (761 aa)
           
  0.533
ITFG1
T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family (612 aa)
           
  0.532
FOCAD
Focadhesin; Potential tumor suppressor in gliomas; Armadillo-like helical domain containing (1801 aa)
           
  0.531
CCBL2
Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se- conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2- oxoglutarate as amino group acceptor (in vitro) (By s [...] (454 aa)
           
  0.530
SNTG1
Gamma-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation; Belongs to the syntrophin family (517 aa)
           
  0.473
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family (205 aa)
           
  0.456
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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