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  • 11.0 [archived version]
STRINGSTRING
CRLF1 CRLF1 FOXG1 FOXG1 FRMD7 FRMD7 FGF14 FGF14 JRK JRK ME2 ME2 SGCE SGCE CAMP CAMP RASAL3 RASAL3 FAM102B FAM102B TRAPPC5 TRAPPC5
"JRK" - Jerky protein homolog in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JRKJerky protein homolog; May bind DNA; Belongs to the tigger transposable element derived protein family (568 aa)    
Predicted Functional Partners:
FOXG1
Forkhead box protein G1; Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon; Forkhead boxes (489 aa)
            
  0.644
ME2
NAD-dependent malic enzyme, mitochondrial; Malic enzyme 2; Belongs to the malic enzymes family (584 aa)
            
  0.640
SGCE
Epsilon-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (462 aa)
            
  0.629
FAM102B
Protein FAM102B; Family with sequence similarity 102 member B; NT-C2 domain containing (360 aa)
            
  0.614
RASAL3
RAS protein activator like-3; Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down-stream ERK signaling pathway; C2 and RasGAP domain containing (1011 aa)
            
  0.613
TRAPPC5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (188 aa)
            
  0.588
CRLF1
Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing (422 aa)
            
  0.540
FGF14
Fibroblast growth factor 14; Probably involved in nervous system development and function; Belongs to the heparin-binding growth factors family (252 aa)
            
  0.539
FRMD7
FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability; FERM domain containing (714 aa)
            
  0.539
CAMP
Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Endogenous ligands (173 aa)
            
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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