| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C5orf45 | FLJ22184 | ENSP00000292586 | ENSP00000482374 | MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.628 |
| CDC45 | FLJ22184 | ENSP00000405726 | ENSP00000482374 | Cell division control protein 45 homolog; Required for initiation of chromosomal DNA replication | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.581 |
| CFAP46 | FAM179A | ENSP00000357575 | ENSP00000368876 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A | 0.530 |
| CFAP46 | FLJ22184 | ENSP00000357575 | ENSP00000482374 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.571 |
| CFAP46 | OVCH1 | ENSP00000357575 | ENSP00000326708 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Ovochymase-1; Ovochymase 1 | 0.539 |
| EVI5L | FLJ22184 | ENSP00000445905 | ENSP00000482374 | EVI5-like protein; Functions as a GTPase-activating protein (GAP) with a broad specificity | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.630 |
| FAM179A | CFAP46 | ENSP00000368876 | ENSP00000357575 | TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.530 |
| FAM179A | FLJ22184 | ENSP00000368876 | ENSP00000482374 | TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.558 |
| FAM179A | OVCH1 | ENSP00000368876 | ENSP00000326708 | TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A | Ovochymase-1; Ovochymase 1 | 0.530 |
| FLJ22184 | C5orf45 | ENSP00000482374 | ENSP00000292586 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair | 0.628 |
| FLJ22184 | CDC45 | ENSP00000482374 | ENSP00000405726 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Cell division control protein 45 homolog; Required for initiation of chromosomal DNA replication | 0.581 |
| FLJ22184 | CFAP46 | ENSP00000482374 | ENSP00000357575 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.571 |
| FLJ22184 | EVI5L | ENSP00000482374 | ENSP00000445905 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | EVI5-like protein; Functions as a GTPase-activating protein (GAP) with a broad specificity | 0.630 |
| FLJ22184 | FAM179A | ENSP00000482374 | ENSP00000368876 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A | 0.558 |
| FLJ22184 | MEDAG | ENSP00000482374 | ENSP00000369849 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Mesenteric estrogen-dependent adipogenesis protein; Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes | 0.628 |
| FLJ22184 | MYD88 | ENSP00000482374 | ENSP00000401399 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintena [...] | 0.628 |
| FLJ22184 | OVCH1 | ENSP00000482374 | ENSP00000326708 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Ovochymase-1; Ovochymase 1 | 0.570 |
| FLJ22184 | PCGF3 | ENSP00000482374 | ENSP00000354724 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Polycomb group RING finger protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Plays a redundant role with PCGF5 as part of a PRC1-like complex that mediates mon [...] | 0.551 |
| FLJ22184 | ZNF445 | ENSP00000482374 | ENSP00000413073 | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | Zinc finger protein 445; May be involved in transcriptional regulation; SCAN domain containing | 0.560 |
| MEDAG | FLJ22184 | ENSP00000369849 | ENSP00000482374 | Mesenteric estrogen-dependent adipogenesis protein; Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes | Proline-rich protein 36; Putative uncharacterized protein FLJ22184 | 0.628 |
