ABCG4 protein (human) - STRING database

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ABCG4

ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G (646 aa)

Predicted Functional Partners:

ABCC11

0.918

ABCC5

0.847

ABCC3

0.758

RUSC2

0.715

ABCF3

0.707

ABCC4

0.703

ABCC2

0.700

AMN

0.673

ABCF2

0.668

CUBN

0.659

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC11	ABCF2	ENSP00000378230	ENSP00000222388	ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...]	ATP binding cassette subfamily F member 2	0.603
ABCC11	ABCF3	ENSP00000378230	ENSP00000411471	ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...]	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	0.514
ABCC11	ABCG4	ENSP00000378230	ENSP00000481728	ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...]	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.918
ABCC2	ABCF2	ENSP00000359478	ENSP00000222388	Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter; ATP binding cassette subfamily C	ATP binding cassette subfamily F member 2	0.570
ABCC2	ABCF3	ENSP00000359478	ENSP00000411471	Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter; ATP binding cassette subfamily C	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	0.508
ABCC2	ABCG4	ENSP00000359478	ENSP00000481728	Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter; ATP binding cassette subfamily C	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.700
ABCC3	ABCF3	ENSP00000285238	ENSP00000411471	Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	0.523
ABCC3	ABCG4	ENSP00000285238	ENSP00000481728	Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.758
ABCC4	ABCG4	ENSP00000366084	ENSP00000481728	Multidrug resistance-associated protein 4; May be an organic anion pump relevant to cellular detoxification; ATP binding cassette subfamily C	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.703
ABCC5	ABCF2	ENSP00000333926	ENSP00000222388	Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	ATP binding cassette subfamily F member 2	0.744
ABCC5	ABCF3	ENSP00000333926	ENSP00000411471	Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	0.544
ABCC5	ABCG4	ENSP00000333926	ENSP00000481728	Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.847
ABCF2	ABCC11	ENSP00000222388	ENSP00000378230	ATP binding cassette subfamily F member 2	ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...]	0.603
ABCF2	ABCC2	ENSP00000222388	ENSP00000359478	ATP binding cassette subfamily F member 2	Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter; ATP binding cassette subfamily C	0.570
ABCF2	ABCC5	ENSP00000222388	ENSP00000333926	ATP binding cassette subfamily F member 2	Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	0.744
ABCF2	ABCF3	ENSP00000222388	ENSP00000411471	ATP binding cassette subfamily F member 2	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	0.569
ABCF2	ABCG4	ENSP00000222388	ENSP00000481728	ATP binding cassette subfamily F member 2	ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G	0.668
ABCF3	ABCC11	ENSP00000411471	ENSP00000378230	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S- conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D- glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...]	0.514
ABCF3	ABCC2	ENSP00000411471	ENSP00000359478	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	Canalicular multispecific organic anion transporter 1; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter; ATP binding cassette subfamily C	0.508
ABCF3	ABCC3	ENSP00000411471	ENSP00000285238	ATP-binding cassette sub-family F member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B; ATP binding cassette subfamily F	Canalicular multispecific organic anion transporter 2; May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity); Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily	0.523

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