FADS6 protein (human) - STRING database

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FADS6

Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family (368 aa)

Predicted Functional Partners:

ACOT1

0.904

ACOT2

0.904

ACOT4

0.903

USH1G

0.797

HID1

0.626

TMEM128

0.626

CDR2L

0.626

OTOP2

0.626

CYB561

0.545

MECR

0.535

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT1	ACOT2	ENSP00000311224	ENSP00000238651	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	0.962
ACOT1	ACOT4	ENSP00000311224	ENSP00000323071	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	0.824
ACOT1	FADS6	ENSP00000311224	ENSP00000481684	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.904
ACOT2	ACOT1	ENSP00000238651	ENSP00000311224	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	0.962
ACOT2	ACOT4	ENSP00000238651	ENSP00000323071	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	0.911
ACOT2	FADS6	ENSP00000238651	ENSP00000481684	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.904
ACOT4	ACOT1	ENSP00000323071	ENSP00000311224	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	0.824
ACOT4	ACOT2	ENSP00000323071	ENSP00000238651	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	0.911
ACOT4	FADS6	ENSP00000323071	ENSP00000481684	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.903
CDR2L	FADS6	ENSP00000336587	ENSP00000481684	Cerebellar degeneration related protein 2 like	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.626
CDR2L	HID1	ENSP00000336587	ENSP00000413520	Cerebellar degeneration related protein 2 like	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	0.709
CDR2L	OTOP2	ENSP00000336587	ENSP00000332528	Cerebellar degeneration related protein 2 like	Otopetrin-2; Otopetrin 2	0.792
CDR2L	TMEM128	ENSP00000336587	ENSP00000372201	Cerebellar degeneration related protein 2 like	Transmembrane protein 128	0.736
CYB561	FADS6	ENSP00000376702	ENSP00000481684	Cytochrome b561; Secretory vesicle-specific electron transport protein; Cytochrome b561	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.545
FADS6	ACOT1	ENSP00000481684	ENSP00000311224	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Acyl-coenzyme A thioesterase 1; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity)	0.904
FADS6	ACOT2	ENSP00000481684	ENSP00000238651	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Acyl-coenzyme A thioesterase 2, mitochondrial; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs	0.904
FADS6	ACOT4	ENSP00000481684	ENSP00000323071	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs; Belongs to the C/M/P thioester hydrolase family	0.903
FADS6	CDR2L	ENSP00000481684	ENSP00000336587	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Cerebellar degeneration related protein 2 like	0.626
FADS6	CYB561	ENSP00000481684	ENSP00000376702	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Cytochrome b561; Secretory vesicle-specific electron transport protein; Cytochrome b561	0.545
FADS6	HID1	ENSP00000481684	ENSP00000413520	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	0.626

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