node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1B1 | EWSR1 | ENSP00000350199 | ENSP00000400142 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family | 0.532 |
AP1B1 | GAS2L1 | ENSP00000350199 | ENSP00000481012 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.762 |
AP1B1 | RASL10A | ENSP00000350199 | ENSP00000216101 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | Ras-like protein family member 10A; Potent inhibitor of cellular proliferation; RAS type GTPase family | 0.838 |
ASCC2 | GAS2L1 | ENSP00000380877 | ENSP00000481012 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.561 |
ASCC2 | ZMAT5 | ENSP00000380877 | ENSP00000344241 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Zinc finger matrin-type 5; U11/U12 di-snRNP | 0.544 |
ENSG00000125954 | GAS2L1 | ENSP00000447121 | ENSP00000481012 | cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta (EC 2.5.1.58); CHURC1-FNTB readthrough | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.590 |
EWSR1 | AP1B1 | ENSP00000400142 | ENSP00000350199 | RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.532 |
EWSR1 | GAS2L1 | ENSP00000400142 | ENSP00000481012 | RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.673 |
EWSR1 | RASL10A | ENSP00000400142 | ENSP00000216101 | RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family | Ras-like protein family member 10A; Potent inhibitor of cellular proliferation; RAS type GTPase family | 0.711 |
GAS2L1 | AP1B1 | ENSP00000481012 | ENSP00000350199 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.762 |
GAS2L1 | ASCC2 | ENSP00000481012 | ENSP00000380877 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.561 |
GAS2L1 | ENSG00000125954 | ENSP00000481012 | ENSP00000447121 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta (EC 2.5.1.58); CHURC1-FNTB readthrough | 0.590 |
GAS2L1 | EWSR1 | ENSP00000481012 | ENSP00000400142 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family | 0.673 |
GAS2L1 | LIPI | ENSP00000481012 | ENSP00000343331 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Lipase member I; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family | 0.716 |
GAS2L1 | MAPRE1 | ENSP00000481012 | ENSP00000364721 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...] | 0.710 |
GAS2L1 | MAPRE3 | ENSP00000481012 | ENSP00000233121 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Microtubule-associated protein RP/EB family member 3; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized [...] | 0.896 |
GAS2L1 | RASL10A | ENSP00000481012 | ENSP00000216101 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Ras-like protein family member 10A; Potent inhibitor of cellular proliferation; RAS type GTPase family | 0.905 |
GAS2L1 | SPA17 | ENSP00000481012 | ENSP00000432305 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.712 |
GAS2L1 | ZMAT5 | ENSP00000481012 | ENSP00000344241 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | Zinc finger matrin-type 5; U11/U12 di-snRNP | 0.574 |
LIPI | GAS2L1 | ENSP00000343331 | ENSP00000481012 | Lipase member I; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.716 |