C20orf195 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C20orf195

Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195 (318 aa)

Predicted Functional Partners:

ZGPAT

0.615

C11orf70

0.537

GMEB2

0.532

UBL4B

0.524

ARFRP1

0.518

COL26A1

0.504

C2orf69

0.495

ZNF558

0.494

FSCN3

0.478

NOL4

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARFRP1	C20orf195	ENSP00000483486	ENSP00000480914	ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	0.518
ARFRP1	GMEB2	ENSP00000483486	ENSP00000266068	ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family	Glucocorticoid modulatory element-binding protein 2; Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses	0.547
ARFRP1	ZGPAT	ENSP00000483486	ENSP00000332013	ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family	Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5’- GGAG[GA]A[GA]A-3’ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis; G-patch domain containing	0.724
C11orf70	C20orf195	ENSP00000414390	ENSP00000480914	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	0.537
C11orf70	C2orf69	ENSP00000414390	ENSP00000312770	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	UPF0565 protein C2orf69; Chromosome 2 open reading frame 69	0.518
C11orf70	FSCN3	ENSP00000414390	ENSP00000265825	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family	0.492
C11orf70	NOL4	ENSP00000414390	ENSP00000261592	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	Nucleolar protein 4	0.480
C11orf70	UBL4B	ENSP00000414390	ENSP00000334044	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	Ubiquitin-like protein 4B; Ubiquitin like 4B	0.520
C11orf70	ZNF558	ENSP00000414390	ENSP00000471277	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	Zinc finger protein 558; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.493
C20orf195	ARFRP1	ENSP00000480914	ENSP00000483486	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family	0.518
C20orf195	C11orf70	ENSP00000480914	ENSP00000414390	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	0.537
C20orf195	C2orf69	ENSP00000480914	ENSP00000312770	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	UPF0565 protein C2orf69; Chromosome 2 open reading frame 69	0.495
C20orf195	COL26A1	ENSP00000480914	ENSP00000318234	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Collagen type XXVI alpha 1 chain; Collagens	0.504
C20orf195	FSCN3	ENSP00000480914	ENSP00000265825	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family	0.478
C20orf195	GMEB2	ENSP00000480914	ENSP00000266068	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Glucocorticoid modulatory element-binding protein 2; Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses	0.532
C20orf195	NOL4	ENSP00000480914	ENSP00000261592	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Nucleolar protein 4	0.471
C20orf195	UBL4B	ENSP00000480914	ENSP00000334044	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Ubiquitin-like protein 4B; Ubiquitin like 4B	0.524
C20orf195	ZGPAT	ENSP00000480914	ENSP00000332013	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5’- GGAG[GA]A[GA]A-3’ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis; G-patch domain containing	0.615
C20orf195	ZNF558	ENSP00000480914	ENSP00000471277	Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195	Zinc finger protein 558; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.494
C2orf69	C11orf70	ENSP00000312770	ENSP00000414390	UPF0565 protein C2orf69; Chromosome 2 open reading frame 69	Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70	0.518

page 1 of 3

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About