• Version:
  • 11.0 [archived version]
STRINGSTRING
TEAD3 TEAD3 N4BP2 N4BP2 C2orf82 C2orf82 ZNF385C ZNF385C SMPX SMPX FOXI2 FOXI2 CRLF1 CRLF1
"ZNF385C" - Zinc finger protein 385C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF385CZinc finger protein 385C (424 aa)    
Predicted Functional Partners:
C2orf82
Uncharacterized protein C2orf82; Chromosome 2 open reading frame 82 (121 aa)
           
  0.587
SMPX
Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes (88 aa)
           
  0.503
FOXI2
Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes (318 aa)
           
  0.474
CRLF1
Cytokine receptor-like factor 1; Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development; Fibronectin type III domain containing (422 aa)
           
  0.453
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell [...] (435 aa)
           
  0.414
N4BP2
NEDD4-binding protein 2; Has 5’-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination (1770 aa)
           
  0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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