| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC11 | CFAP57 | ENSP00000381553 | ENSP00000479773 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis | Cilia and flagella associated protein 57 | 0.729 |
| CCDC74A | CFAP57 | ENSP00000295171 | ENSP00000479773 | Coiled-coil domain containing 74A | Cilia and flagella associated protein 57 | 0.622 |
| CCDC74A | FAM132B | ENSP00000295171 | ENSP00000442304 | Coiled-coil domain containing 74A | Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage- produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake; Belongs to the adipolin/erythroferrone family | 0.465 |
| CCDC74A | SDSL | ENSP00000295171 | ENSP00000385790 | Coiled-coil domain containing 74A | Serine dehydratase-like; Has low serine dehydratase and threonine dehydratase activity | 0.435 |
| CCDC74A | SLC25A21 | ENSP00000295171 | ENSP00000329452 | Coiled-coil domain containing 74A | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.542 |
| CCDC74A | TMEM56 | ENSP00000295171 | ENSP00000359222 | Coiled-coil domain containing 74A | Transmembrane protein 56; TLC domain containing | 0.597 |
| CFAP57 | CCDC11 | ENSP00000479773 | ENSP00000381553 | Cilia and flagella associated protein 57 | Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis | 0.729 |
| CFAP57 | CCDC74A | ENSP00000479773 | ENSP00000295171 | Cilia and flagella associated protein 57 | Coiled-coil domain containing 74A | 0.622 |
| CFAP57 | DHX35 | ENSP00000479773 | ENSP00000252011 | Cilia and flagella associated protein 57 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | 0.549 |
| CFAP57 | FAM132B | ENSP00000479773 | ENSP00000442304 | Cilia and flagella associated protein 57 | Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage- produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake; Belongs to the adipolin/erythroferrone family | 0.511 |
| CFAP57 | FAM162B | ENSP00000479773 | ENSP00000357545 | Cilia and flagella associated protein 57 | Protein FAM162B; Family with sequence similarity 162 member B | 0.511 |
| CFAP57 | PELI2 | ENSP00000479773 | ENSP00000267460 | Cilia and flagella associated protein 57 | E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 ’Lys-63’-linked polyubiquitination and possibly ’Lys-48’-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1 | 0.559 |
| CFAP57 | SDSL | ENSP00000479773 | ENSP00000385790 | Cilia and flagella associated protein 57 | Serine dehydratase-like; Has low serine dehydratase and threonine dehydratase activity | 0.545 |
| CFAP57 | SLC25A21 | ENSP00000479773 | ENSP00000329452 | Cilia and flagella associated protein 57 | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.591 |
| CFAP57 | TMEM56 | ENSP00000479773 | ENSP00000359222 | Cilia and flagella associated protein 57 | Transmembrane protein 56; TLC domain containing | 0.554 |
| CFAP57 | ZNF676 | ENSP00000479773 | ENSP00000380310 | Cilia and flagella associated protein 57 | Zinc finger protein 676; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.565 |
| DHX35 | CFAP57 | ENSP00000252011 | ENSP00000479773 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | Cilia and flagella associated protein 57 | 0.549 |
| DHX35 | PELI2 | ENSP00000252011 | ENSP00000267460 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | E3 ubiquitin-protein ligase pellino homolog 2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 ’Lys-63’-linked polyubiquitination and possibly ’Lys-48’-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1 | 0.420 |
| DHX35 | ZNF676 | ENSP00000252011 | ENSP00000380310 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | Zinc finger protein 676; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.516 |
| FAM132B | CCDC74A | ENSP00000442304 | ENSP00000295171 | Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage- produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake; Belongs to the adipolin/erythroferrone family | Coiled-coil domain containing 74A | 0.465 |
