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STRINGSTRING
IGSF11 IGSF11 GPATCH2 GPATCH2 LYPD6B LYPD6B ENSG00000278289 ENSG00000278289 FAM133A FAM133A DNAJB8 DNAJB8 PRSS55 PRSS55 FBXO39 FBXO39 SPAG8 SPAG8 TEPP TEPP ODF4 ODF4
"ENSG00000278289" - Cancer/testis antigen family 45 member A6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ENSG00000278289Cancer/testis antigen family 45 member A6 (189 aa)    
Predicted Functional Partners:
FAM133A
Protein FAM133A; Family with sequence similarity 133 member A (248 aa)
      
   
  0.642
FBXO39
F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other (442 aa)
      
   
  0.595
GPATCH2
G patch domain-containing protein 2; Enhances the ATPase activity of DHX15 in vitro; G-patch domain containing (528 aa)
      
   
  0.583
SPAG8
Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis. May play a role in fertility and microtubule formation through interaction with RANBP9 [...] (501 aa)
            
  0.579
LYPD6B
Ly6/PLAUR domain-containing protein 6B; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifally alpha-3(3)-beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2)-alpha- 5-beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn- 398 but not its wild-type sequence; LY6/PLAUR domain containing (207 aa)
            
  0.576
PRSS55
Serine protease 55; Probable serine protease (352 aa)
            
  0.527
IGSF11
Immunoglobulin superfamily member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth; I-set domain containing (431 aa)
            
  0.517
TEPP
Testis, prostate and placenta expressed (298 aa)
            
  0.511
DNAJB8
DnaJ homolog subfamily B member 8; Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins; DNAJ heat shock proteins (232 aa)
      
   
  0.501
ODF4
Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton (257 aa)
            
  0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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