• Version:
  • 11.0 [archived version]
STRINGSTRING
RILPL1 RILPL1 NEDD4 NEDD4 GUCD1 GUCD1 SLC2A11 SLC2A11 DRICH1 DRICH1 RGL4 RGL4 C22orf15 C22orf15 LRRC75B LRRC75B UPB1 UPB1 SPECC1L SPECC1L ZNF70 ZNF70
"GUCD1" - Protein GUCD1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GUCD1Protein GUCD1; Guanylyl cyclase domain containing 1 (296 aa)    
Predicted Functional Partners:
LRRC75B
Leucine-rich repeat-containing protein 75B; Leucine rich repeat containing 75B (315 aa)
           
  0.706
C22orf15
Uncharacterized protein C22orf15; Chromosome 22 open reading frame 15 (148 aa)
           
  0.670
DRICH1
Aspartate-rich protein 1; Aspartate rich 1 (229 aa)
           
  0.668
ZNF70
Zinc finger protein 70; May be involved in transcriptional regulation; Zinc fingers C2H2-type (446 aa)
           
  0.651
NEDD4
E3 ubiquitin-protein ligase NEDD4; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Specifically ubiquitinates ’Lys-63’ in target proteins. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. [...] (1319 aa)
       
 
  0.592
RGL4
Ral-GDS-related protein; Ral guanine nucleotide dissociation stimulator like 4 (473 aa)
           
  0.587
RILPL1
RILP-like protein 1; Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution; Belongs to the RILPL family (403 aa)
           
  0.535
SPECC1L
Cytospin-A; Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration; Belongs to the cytospin-A family (1117 aa)
           
  0.535
UPB1
Beta-ureidopropionase; Converts N-carbamoyl-beta-aminoisobutyrate and N- carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide (384 aa)
           
  0.495
SLC2A11
Solute carrier family 2, facilitated glucose transporter member 11; Facilitative glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily (535 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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