node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALS2CR11 | RIMBP3 | ENSP00000409937 | ENSP00000483386 | C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.496 |
ALS2CR11 | RIMBP3B | ENSP00000409937 | ENSP00000479326 | C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 | RIMS binding protein 3B | 0.560 |
ALS2CR11 | RIMBP3C | ENSP00000409937 | ENSP00000390630 | C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 | RIMS binding protein 3C; Belongs to the RIMBP family | 0.577 |
ALS2CR11 | TSACC | ENSP00000409937 | ENSP00000357238 | C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 | TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family | 0.606 |
ATP5L2 | CECR6 | ENSP00000421076 | ENSP00000329318 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | 0.571 |
ATP5L2 | DDTL | ENSP00000421076 | ENSP00000215770 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.593 |
ATP5L2 | RIMBP3 | ENSP00000421076 | ENSP00000483386 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.489 |
ATP5L2 | RIMBP3B | ENSP00000421076 | ENSP00000479326 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | RIMS binding protein 3B | 0.570 |
ATP5L2 | SLC35E4 | ENSP00000421076 | ENSP00000339626 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | Solute carrier family 35 member E4; Putative transporter; Solute carriers | 0.648 |
CECR6 | ATP5L2 | ENSP00000329318 | ENSP00000421076 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | 0.571 |
CECR6 | DDTL | ENSP00000329318 | ENSP00000215770 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.560 |
CECR6 | RIMBP3 | ENSP00000329318 | ENSP00000483386 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.474 |
CECR6 | RIMBP3B | ENSP00000329318 | ENSP00000479326 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | RIMS binding protein 3B | 0.559 |
CECR6 | SLC35E4 | ENSP00000329318 | ENSP00000339626 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | Solute carrier family 35 member E4; Putative transporter; Solute carriers | 0.631 |
DDTL | ATP5L2 | ENSP00000215770 | ENSP00000421076 | D-dopachrome decarboxylase-like protein; May have lyase activity | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | 0.593 |
DDTL | CECR6 | ENSP00000215770 | ENSP00000329318 | D-dopachrome decarboxylase-like protein; May have lyase activity | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | 0.560 |
DDTL | RIMBP3 | ENSP00000215770 | ENSP00000483386 | D-dopachrome decarboxylase-like protein; May have lyase activity | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.475 |
DDTL | RIMBP3B | ENSP00000215770 | ENSP00000479326 | D-dopachrome decarboxylase-like protein; May have lyase activity | RIMS binding protein 3B | 0.560 |
DDTL | SLC35E4 | ENSP00000215770 | ENSP00000339626 | D-dopachrome decarboxylase-like protein; May have lyase activity | Solute carrier family 35 member E4; Putative transporter; Solute carriers | 0.634 |
MAPK8IP1 | MAPK8IP2 | ENSP00000241014 | ENSP00000330572 | C-Jun-amino-terminal kinase-interacting protein 1; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK- regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. [...] | C-Jun-amino-terminal kinase-interacting protein 2; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity) | 0.972 |