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  • 11.0 [archived version]
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TMEM177 TMEM177 IL4I1 IL4I1 IFNLR1 IFNLR1 GRXCR2 GRXCR2 GABBR1 GABBR1 JAKMIP2 JAKMIP2 YIPF5 YIPF5 STK32A STK32A SRRM4 SRRM4 VAT1L VAT1L THSD7A THSD7A
"JAKMIP2" - Janus kinase and microtubule interacting protein 2 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JAKMIP2Janus kinase and microtubule interacting protein 2; Belongs to the JAKMIP family (820 aa)    
Predicted Functional Partners:
STK32A
Serine/threonine kinase 32A (407 aa)
     
   
  0.787
GABBR1
Gamma-aminobutyric acid type B receptor subunit 1; Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-depend [...] (961 aa)
     
 
  0.655
IL4I1
L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity); Belongs to the flavin monoamine oxidase family. FIG1 subfamily (589 aa)
           
  0.588
VAT1L
Synaptic vesicle membrane protein VAT-1 homolog-like; Vesicle amine transport 1 like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily (419 aa)
     
   
  0.582
SRRM4
Serine/arginine repetitive matrix protein 4; Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural- specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity) (611 aa)
     
   
  0.549
THSD7A
Thrombospondin type-1 domain-containing protein 7A; The soluble form promotes endothelial cell migration and filopodia formationduring angiogenesis via a FAK-dependent mechanism (1657 aa)
     
   
  0.529
TMEM177
Transmembrane protein 177 (311 aa)
           
  0.519
IFNLR1
Interferon lambda receptor 1; The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, [...] (520 aa)
           
  0.517
GRXCR2
Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Deafness associated genes (248 aa)
           
  0.517
YIPF5
Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Yip1 domain containing (257 aa)
           
  0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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