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  • 11.0 [archived version]
STRINGSTRING
ZNF865 ZNF865 FAM178B FAM178B RAB3IL1 RAB3IL1 TMEM200C TMEM200C ZNF48 ZNF48 PTMS PTMS PTMA PTMA TPR TPR TMSB4X TMSB4X NANS NANS LGALS9C LGALS9C
"PTMS" - Parathymosin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PTMSParathymosin; Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections (102 aa)    
Predicted Functional Partners:
PTMA
Prothymosin alpha; Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections (111 aa)
      
 
  0.981
NANS
Sialic acid synthase; Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively (359 aa)
      
   
  0.672
FAM178B
Protein FAM178B; Family with sequence similarity 178 member B (679 aa)
            
  0.553
TMEM200C
Transmembrane protein 200C (621 aa)
            
  0.542
RAB3IL1
Guanine nucleotide exchange factor for Rab-3A; Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B; Belongs to the SEC2 family (382 aa)
      
   
  0.525
TMSB4X
Thymosin beta-4; Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (44 aa)
            
  0.511
ZNF48
Zinc finger protein 48; May be involved in transcriptional regulation; Zinc fingers C2H2-type (618 aa)
      
   
  0.480
LGALS9C
Galectin-9C; Binds galactosides; Galectins (356 aa)
            
  0.459
TPR
Nucleoprotein TPR; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates the nuclear export of unspliced mRNA [...] (2363 aa)
      
   
  0.457
ZNF865
Zinc finger protein 865; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1059 aa)
      
   
  0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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