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  • 11.0 [archived version]
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GLB1L2 GLB1L2 PNPLA7 PNPLA7 PLEKHA5 PLEKHA5 TRIM28 TRIM28 ZNF714 ZNF714 ERICH1 ERICH1 PCDHGB2 PCDHGB2 CCDC51 CCDC51 ATAD3C ATAD3C C8orf44 C8orf44 CYB5RL CYB5RL
"ZNF714" - Zinc finger protein 714 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF714Zinc finger protein 714; May be involved in transcriptional regulation; Zinc fingers C2H2-type (555 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.914
CYB5RL
NADH-cytochrome b5 reductase-like; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (315 aa)
     
   
  0.659
C8orf44
Putative uncharacterized protein C8orf44; Chromosome 8 open reading frame 44 (159 aa)
           
  0.658
ATAD3C
ATPase family, AAA domain containing 3C; Belongs to the AAA ATPase family (411 aa)
           
  0.590
CCDC51
Coiled-coil domain containing 51 (411 aa)
           
  0.539
PCDHGB2
Protocadherin gamma-B2; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (931 aa)
       
 
  0.475
GLB1L2
Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2 (636 aa)
           
  0.473
ERICH1
Glutamate-rich protein 1; Glutamate rich 1 (443 aa)
           
  0.450
PNPLA7
Patatin-like phospholipase domain-containing protein 7; Serine hydrolase, whose specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy; Patatin like phospholipase domain containing (1342 aa)
     
 
  0.442
PLEKHA5
Pleckstrin homology domain containing A5 (1282 aa)
     
 
  0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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