• Version:
  • 11.0 [archived version]
STRINGSTRING
AAMP AAMP PCDHGB1 PCDHGB1 PCDHGB4 PCDHGB4 ITIH5 ITIH5 PCDHGB5 PCDHGB5 ADAM11 ADAM11 LAMC3 LAMC3 CADM3 CADM3 TJAP1 TJAP1
"PCDHGB5" - Protocadherin gamma-B5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
PCDHGB5Protocadherin gamma-B5; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (923 aa)    
Predicted Functional Partners:
PCDHGB1
Protocadherin gamma-B1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (927 aa)
     
 
0.713
PCDHGB4
Protocadherin gamma-B4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (923 aa)
     
 
0.634
AAMP
Angio-associated migratory cell protein; Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway; WD repeat domain containing (434 aa)
           
  0.457
ADAM11
Disintegrin and metalloproteinase domain-containing protein 11; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing (769 aa)
     
   
  0.437
ITIH5
Inter-alpha-trypsin inhibitor heavy chain H5; May act as a tumor suppressor (942 aa)
           
  0.418
TJAP1
Tight junction associated protein 1 (557 aa)
           
  0.410
LAMC3
Laminin subunit gamma-3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (1575 aa)
           
  0.408
CADM3
Cell adhesion molecule 3; Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity); C2-set domain containing (432 aa)
           
  0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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