ENSG00000276345 protein (human)

Nodes:

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second shell of interactors

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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Score

ENSG00000276345

Mitochondrial ribosomal protein L23 (153 aa)

Predicted Functional Partners:

MRPL44

0.936

MRPL15

0.932

MRPL47

0.902

MRPS16

0.876

MRPL41

0.857

MRPL4

0.855

MRPL54

0.843

MRPS34

0.832

MRPS12

0.829

MRPL3

0.803

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000276345	MRPL15	ENSP00000478035	ENSP00000260102	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein L15	0.932
ENSG00000276345	MRPL3	ENSP00000478035	ENSP00000264995	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein L3	0.803
ENSG00000276345	MRPL4	ENSP00000478035	ENSP00000253099	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.855
ENSG00000276345	MRPL41	ENSP00000478035	ENSP00000360498	Mitochondrial ribosomal protein L23	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.857
ENSG00000276345	MRPL44	ENSP00000478035	ENSP00000258383	Mitochondrial ribosomal protein L23	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.936
ENSG00000276345	MRPL47	ENSP00000478035	ENSP00000417602	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein L47	0.902
ENSG00000276345	MRPL54	ENSP00000478035	ENSP00000331849	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein L54	0.843
ENSG00000276345	MRPS12	ENSP00000478035	ENSP00000384952	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein S12	0.829
ENSG00000276345	MRPS16	ENSP00000478035	ENSP00000362036	Mitochondrial ribosomal protein L23	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.876
ENSG00000276345	MRPS34	ENSP00000478035	ENSP00000177742	Mitochondrial ribosomal protein L23	28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation	0.832
MRPL15	ENSG00000276345	ENSP00000260102	ENSP00000478035	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein L23	0.932
MRPL15	MRPL3	ENSP00000260102	ENSP00000264995	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein L3	0.999
MRPL15	MRPL4	ENSP00000260102	ENSP00000253099	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.999
MRPL15	MRPL41	ENSP00000260102	ENSP00000360498	Mitochondrial ribosomal protein L15	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.998
MRPL15	MRPL44	ENSP00000260102	ENSP00000258383	Mitochondrial ribosomal protein L15	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.996
MRPL15	MRPL47	ENSP00000260102	ENSP00000417602	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein L47	0.999
MRPL15	MRPL54	ENSP00000260102	ENSP00000331849	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein L54	0.990
MRPL15	MRPS12	ENSP00000260102	ENSP00000384952	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein S12	0.997
MRPL15	MRPS16	ENSP00000260102	ENSP00000362036	Mitochondrial ribosomal protein L15	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.998
MRPL15	MRPS34	ENSP00000260102	ENSP00000177742	Mitochondrial ribosomal protein L15	28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation	0.978

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