• Version:
  • 11.0 [archived version]
STRINGSTRING
TSKU TSKU EPDR1 EPDR1 DNPH1 DNPH1 TMEM52B TMEM52B CLEC18C CLEC18C TMEM72 TMEM72 SMIM34B SMIM34B C1QTNF9B C1QTNF9B C9orf66 C9orf66 EWSR1 EWSR1 FUS FUS
"CLEC18C" - C-type lectin domain family 18 member C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLEC18CC-type lectin domain family 18 member C; Binds polysaccharidesin a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans; C-type lectin domain containing (446 aa)    
Predicted Functional Partners:
SMIM34B
annotation not available (139 aa)
           
  0.589
C1QTNF9B
Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B (333 aa)
           
  0.510
TMEM52B
Transmembrane protein 52B (183 aa)
           
  0.495
C9orf66
Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66 (295 aa)
           
  0.475
TMEM72
Transmembrane protein 72 (275 aa)
           
  0.448
TSKU
Tsukushin; Tsukushi, small leucine rich proteoglycan (353 aa)
       
 
  0.443
EPDR1
Mammalian ependymin-related protein 1; Ependymin related 1 (224 aa)
           
  0.442
DNPH1
2’-deoxynucleoside 5’-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5’-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5’- monophosphates containing purine bases are preferred to those containing pyrimidine bases (174 aa)
           
  0.424
EWSR1
RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family (661 aa)
           
  0.417
FUS
RNA-binding protein FUS; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity; Belongs to the RRM TET family (526 aa)
           
  0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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