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STRINGSTRING
C10orf76 C10orf76 ICA1L ICA1L MTUS2 MTUS2 ASCL5 ASCL5 KCNN2 KCNN2 ZNF316 ZNF316 ZNF148 ZNF148 HDDC2 HDDC2 C2orf68 C2orf68 NDOR1 NDOR1 METTL15 METTL15
"ZNF316" - Zinc finger protein 316 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
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[Homology]
Score
ZNF316Zinc finger protein 316; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1004 aa)    
Predicted Functional Partners:
C2orf68
UPF0561 protein C2orf68; Chromosome 2 open reading frame 68 (166 aa)
            
  0.610
ASCL5
Achaete-scute homolog 5; Achaete-scute family bHLH transcription factor 5; Basic helix-loop-helix proteins (206 aa)
        
 
  0.603
HDDC2
HD domain containing 2; Belongs to the HDDC2 family (204 aa)
            
  0.588
NDOR1
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins (By similarity). Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1; Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family (606 aa)
      
   
  0.587
METTL15
Probable methyltransferase-like protein 15; Probable S-adenosyl-L-methionine-dependent methyltransferase (407 aa)
            
  0.586
KCNN2
Small conductance calcium-activated potassium channel protein 2; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin; Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily (579 aa)
        
 
  0.559
C10orf76
UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 (689 aa)
            
  0.525
MTUS2
Microtubule-associated tumor suppressor candidate 2; Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip; In the C-terminal section; belongs to the MTUS1 family (1379 aa)
            
  0.524
ICA1L
Islet cell autoantigen 1-like protein; Classical BAR domain containing (482 aa)
            
  0.502
ZNF148
Zinc finger protein 148; Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes; Zinc fingers C2H2-type (794 aa)
        
 
0.496
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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