ZNF595 protein (human) - STRING database

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ZNF595

Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type (648 aa)

Predicted Functional Partners:

TRIM28

0.925

THSD7B

0.649

FOXD4L5

0.600

ANKRD20A2

0.596

FOXD4L3

0.532

OR5M11

0.530

SPOP

0.526

UBTFL1

0.507

OR2T2

0.473

OR4C3

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD20A2	FOXD4L3	ENSP00000366826	ENSP00000341961	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Forkhead box D4 like 3	0.684
ANKRD20A2	FOXD4L5	ENSP00000366826	ENSP00000366637	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Forkhead box D4 like 5	0.720
ANKRD20A2	ZNF595	ENSP00000366826	ENSP00000477392	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.596
FOXD4L3	ANKRD20A2	ENSP00000341961	ENSP00000366826	Forkhead box D4 like 3	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.684
FOXD4L3	ZNF595	ENSP00000341961	ENSP00000477392	Forkhead box D4 like 3	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.532
FOXD4L5	ANKRD20A2	ENSP00000366637	ENSP00000366826	Forkhead box D4 like 5	Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2	0.720
FOXD4L5	ZNF595	ENSP00000366637	ENSP00000477392	Forkhead box D4 like 5	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.600
OR2T2	UBTFL1	ENSP00000343062	ENSP00000485108	Olfactory receptor 2T2; Odorant receptor; Olfactory receptors, family 2	Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development	0.573
OR2T2	ZNF595	ENSP00000343062	ENSP00000477392	Olfactory receptor 2T2; Odorant receptor; Olfactory receptors, family 2	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.473
OR4C3	UBTFL1	ENSP00000321419	ENSP00000485108	Olfactory receptor 4C3; Odorant receptor; Olfactory receptors, family 4	Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development	0.570
OR4C3	ZNF595	ENSP00000321419	ENSP00000477392	Olfactory receptor 4C3; Odorant receptor; Olfactory receptors, family 4	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.471
OR5M11	ZNF595	ENSP00000432417	ENSP00000477392	Olfactory receptor 5M11; Odorant receptor; Olfactory receptors, family 5	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.530
SPOP	THSD7B	ENSP00000377001	ENSP00000272643	Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-base [...]	Thrombospondin type-1 domain-containing protein 7B; Thrombospondin type 1 domain containing 7B	0.426
SPOP	ZNF595	ENSP00000377001	ENSP00000477392	Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-base [...]	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.526
THSD7B	SPOP	ENSP00000272643	ENSP00000377001	Thrombospondin type-1 domain-containing protein 7B; Thrombospondin type 1 domain containing 7B	Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-base [...]	0.426
THSD7B	ZNF595	ENSP00000272643	ENSP00000477392	Thrombospondin type-1 domain-containing protein 7B; Thrombospondin type 1 domain containing 7B	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.649
TRIM28	ZNF595	ENSP00000253024	ENSP00000477392	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.925
UBTFL1	OR2T2	ENSP00000485108	ENSP00000343062	Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development	Olfactory receptor 2T2; Odorant receptor; Olfactory receptors, family 2	0.573
UBTFL1	OR4C3	ENSP00000485108	ENSP00000321419	Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development	Olfactory receptor 4C3; Odorant receptor; Olfactory receptors, family 4	0.570
UBTFL1	ZNF595	ENSP00000485108	ENSP00000477392	Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development	Zinc finger protein 595; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.507

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