• Version:
  • 11.0 [archived version]
STRINGSTRING
SDCBP SDCBP PCDHB7 PCDHB7 PRSS55 PRSS55 PCDHB16 PCDHB16 WFDC3 WFDC3 TMCO3 TMCO3 OR11G2 OR11G2 C5orf15 C5orf15 AMMECR1 AMMECR1 PRSS48 PRSS48 TMTC4 TMTC4
"PCDHB16" - Protocadherin beta-16 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDHB16Protocadherin beta-16; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (776 aa)    
Predicted Functional Partners:
PCDHB7
Protocadherin beta-7; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (793 aa)
     
 
0.680
PRSS48
Serine protease 48; Belongs to the peptidase S1 family (328 aa)
           
  0.518
TMTC4
Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family (760 aa)
     
 
  0.493
OR11G2
Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11 (345 aa)
           
  0.473
SDCBP
Syntenin-1; Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1- mediated SMAD2/3 activation and TGFB1-induced epithelial-to- mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6I [...] (298 aa)
       
 
  0.439
C5orf15
Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 (265 aa)
           
  0.433
PRSS55
Serine protease 55; Probable serine protease (352 aa)
           
  0.427
WFDC3
WAP four-disulfide core domain containing (231 aa)
           
  0.424
TMCO3
Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation-proton antiporter 2 (CPA2) transporter (TC 2.A.37) family (677 aa)
           
  0.417
AMMECR1
AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 (333 aa)
           
  0.411
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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