node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | CCL26 | ENSP00000295897 | ENSP00000378365 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils; Belongs to the intercrine beta (chemokine CC) family | 0.530 |
ALB | COL1A1 | ENSP00000295897 | ENSP00000225964 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | 0.488 |
ALB | DCN | ENSP00000295897 | ENSP00000052754 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | 0.501 |
ALB | PRDM10 | ENSP00000295897 | ENSP00000351686 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | PR domain zinc finger protein 10; May be involved in transcriptional regulation; PR/SET domain family | 0.831 |
ALB | SCX | ENSP00000295897 | ENSP00000476384 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages; Basic helix-loop-helix proteins | 0.571 |
ALB | SOX9 | ENSP00000295897 | ENSP00000245479 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | Transcription factor SOX-9; Transcriptional regulator. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development; SRY-boxes | 0.549 |
CCL26 | ALB | ENSP00000378365 | ENSP00000295897 | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils; Belongs to the intercrine beta (chemokine CC) family | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | 0.530 |
CCL26 | PRDM10 | ENSP00000378365 | ENSP00000351686 | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils; Belongs to the intercrine beta (chemokine CC) family | PR domain zinc finger protein 10; May be involved in transcriptional regulation; PR/SET domain family | 0.441 |
CCL26 | SCX | ENSP00000378365 | ENSP00000476384 | C-C motif chemokine 26; Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils; Belongs to the intercrine beta (chemokine CC) family | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages; Basic helix-loop-helix proteins | 0.588 |
COL1A1 | ALB | ENSP00000225964 | ENSP00000295897 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | 0.488 |
COL1A1 | DCN | ENSP00000225964 | ENSP00000052754 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | 0.966 |
COL1A1 | MKX | ENSP00000225964 | ENSP00000364946 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion; TALE class homeoboxes and pseudogenes | 0.705 |
COL1A1 | SCX | ENSP00000225964 | ENSP00000476384 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages; Basic helix-loop-helix proteins | 0.615 |
COL1A1 | SOX9 | ENSP00000225964 | ENSP00000245479 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Transcription factor SOX-9; Transcriptional regulator. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development; SRY-boxes | 0.715 |
COL1A1 | TNMD | ENSP00000225964 | ENSP00000362122 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | Tenomodulin; May be an angiogenesis inhibitor; BRICHOS domain containing | 0.628 |
DCN | ALB | ENSP00000052754 | ENSP00000295897 | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc; Belongs to the ALB/AFP/VDB family | 0.501 |
DCN | COL1A1 | ENSP00000052754 | ENSP00000225964 | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens | 0.966 |
DCN | GDF7 | ENSP00000052754 | ENSP00000272224 | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | Growth/differentiation factor 7; May play an active role in the motor area of the primate neocortex | 0.487 |
DCN | MKX | ENSP00000052754 | ENSP00000364946 | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion; TALE class homeoboxes and pseudogenes | 0.553 |
DCN | SCX | ENSP00000052754 | ENSP00000476384 | Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans | Basic helix-loop-helix transcription factor scleraxis; Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages; Basic helix-loop-helix proteins | 0.566 |