node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C6orf141 | PDCL3 | ENSP00000434602 | ENSP00000264254 | Uncharacterized protein C6orf141; Chromosome 6 open reading frame 141 | Phosducin-like protein 3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination; Belongs to the phosducin family | 0.522 |
C6orf141 | SMAGP | ENSP00000434602 | ENSP00000475068 | Uncharacterized protein C6orf141; Chromosome 6 open reading frame 141 | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.567 |
C6orf141 | SYNE3 | ENSP00000434602 | ENSP00000334308 | Uncharacterized protein C6orf141; Chromosome 6 open reading frame 141 | Nesprin-3; As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is re [...] | 0.525 |
CEACAM20 | CMTM4 | ENSP00000481937 | ENSP00000333833 | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | CKLF like MARVEL transmembrane domain containing 4 | 0.458 |
CEACAM20 | CNNM1 | ENSP00000481937 | ENSP00000349147 | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | 0.458 |
CEACAM20 | COLGALT2 | ENSP00000481937 | ENSP00000354960 | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family | 0.458 |
CEACAM20 | SMAGP | ENSP00000481937 | ENSP00000475068 | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.499 |
CMTM4 | CEACAM20 | ENSP00000333833 | ENSP00000481937 | CKLF like MARVEL transmembrane domain containing 4 | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | 0.458 |
CMTM4 | CNNM1 | ENSP00000333833 | ENSP00000349147 | CKLF like MARVEL transmembrane domain containing 4 | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | 0.494 |
CMTM4 | COLGALT2 | ENSP00000333833 | ENSP00000354960 | CKLF like MARVEL transmembrane domain containing 4 | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family | 0.488 |
CMTM4 | SMAGP | ENSP00000333833 | ENSP00000475068 | CKLF like MARVEL transmembrane domain containing 4 | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.496 |
CNNM1 | CEACAM20 | ENSP00000349147 | ENSP00000481937 | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | 0.458 |
CNNM1 | CMTM4 | ENSP00000349147 | ENSP00000333833 | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | CKLF like MARVEL transmembrane domain containing 4 | 0.494 |
CNNM1 | COLGALT2 | ENSP00000349147 | ENSP00000354960 | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family | 0.493 |
CNNM1 | SMAGP | ENSP00000349147 | ENSP00000475068 | Metal transporter CNNM1; Probable metal transporter; Belongs to the ACDP family | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.502 |
COL26A1 | COLGALT2 | ENSP00000318234 | ENSP00000354960 | Collagen type XXVI alpha 1 chain; Collagens | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family | 0.903 |
COL26A1 | MITD1 | ENSP00000318234 | ENSP00000289359 | Collagen type XXVI alpha 1 chain; Collagens | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex | 0.471 |
COL26A1 | SMAGP | ENSP00000318234 | ENSP00000475068 | Collagen type XXVI alpha 1 chain; Collagens | Small cell adhesion glycoprotein; May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation | 0.483 |
COL26A1 | TSNAXIP1 | ENSP00000318234 | ENSP00000457241 | Collagen type XXVI alpha 1 chain; Collagens | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis | 0.501 |
COLGALT2 | CEACAM20 | ENSP00000354960 | ENSP00000481937 | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family | Carcinoembryonic antigen-related cell adhesion molecule 20; Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response; Belongs to the immunoglobulin superfamily. CEA family | 0.458 |