• Version:
  • 11.0 [archived version]
STRINGSTRING
ENSG00000270386 ENSG00000270386 MAPRE2 MAPRE2 MAPRE1 MAPRE1 NBPF1 NBPF1 MAPRE3 MAPRE3 MRFAP1 MRFAP1 GAS2L2 GAS2L2 LIPI LIPI ZBTB37 ZBTB37 SPA17 SPA17 RASL10A RASL10A
"GAS2L2" - GAS2-like protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
GAS2L2GAS2-like protein 2; Seems to be involved in the cross-linking of microtubules and microfilaments (880 aa)    
Predicted Functional Partners:
RASL10A
Ras-like protein family member 10A; Potent inhibitor of cellular proliferation; RAS type GTPase family (203 aa)
     
 
  0.808
LIPI
Lipase member I; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family (481 aa)
           
  0.800
SPA17
Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) (151 aa)
           
  0.754
MRFAP1
Morf4 family associated protein 1 (127 aa)
           
  0.645
MAPRE1
Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...] (268 aa)
     
 
  0.631
NBPF1
Neuroblastoma breakpoint family member 1; NBPF member 1 (1139 aa)
           
  0.530
ZBTB37
Zinc finger and BTB domain-containing protein 37; May be involved in transcriptional regulation; BTB domain containing (503 aa)
       
 
  0.510
MAPRE3
Microtubule-associated protein RP/EB family member 3; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized [...] (281 aa)
     
 
  0.506
MAPRE2
Microtubule-associated protein RP/EB family member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity); Belongs to the MAPRE family (327 aa)
     
 
  0.468
ENSG00000270386
UDP-glucuronosyltransferase 2A1; UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus; Belongs to the UDP-glycosyltransferase family (693 aa)
           
  0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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