TMEM120A protein (human) - STRING database

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TMEM120A

Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family (343 aa)

Predicted Functional Partners:

NCLN

0.723

B4GALT3

0.719

PPAPDC3

0.700

ORMDL2

0.671

TMEM177

0.636

MOSPD3

0.602

C1QTNF1

0.597

TM7SF2

0.587

TMEM115

0.583

TMEM59L

0.547

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4GALT3	TMEM120A	ENSP00000480428	ENSP00000473983	Beta-1,4-galactosyltransferase 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Beta 4-glycosyltransferases	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.719
C1QTNF1	TMEM120A	ENSP00000340864	ENSP00000473983	Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.597
MOSPD3	TMEM120A	ENSP00000377522	ENSP00000473983	Motile sperm domain containing 3	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.602
NCLN	TMEM120A	ENSP00000246117	ENSP00000473983	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.723
ORMDL2	TMEM120A	ENSP00000243045	ENSP00000473983	ORM1-like protein 2; Negative regulator of sphingolipid synthesis	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.671
PPAPDC3	TM7SF2	ENSP00000361338	ENSP00000279263	Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity)	Delta(14)-sterol reductase; Involved in the conversion of lanosterol to cholesterol	0.584
PPAPDC3	TMEM120A	ENSP00000361338	ENSP00000473983	Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity)	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.700
TM7SF2	PPAPDC3	ENSP00000279263	ENSP00000361338	Delta(14)-sterol reductase; Involved in the conversion of lanosterol to cholesterol	Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity)	0.584
TM7SF2	TMEM120A	ENSP00000279263	ENSP00000473983	Delta(14)-sterol reductase; Involved in the conversion of lanosterol to cholesterol	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.587
TMEM115	TMEM120A	ENSP00000266025	ENSP00000473983	Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi; Rhomboid family	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	0.583
TMEM115	TMEM177	ENSP00000266025	ENSP00000402661	Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi; Rhomboid family	Transmembrane protein 177	0.655
TMEM115	TMEM59L	ENSP00000266025	ENSP00000470879	Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi; Rhomboid family	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.556
TMEM120A	B4GALT3	ENSP00000473983	ENSP00000480428	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Beta-1,4-galactosyltransferase 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Beta 4-glycosyltransferases	0.719
TMEM120A	C1QTNF1	ENSP00000473983	ENSP00000340864	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1	0.597
TMEM120A	MOSPD3	ENSP00000473983	ENSP00000377522	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Motile sperm domain containing 3	0.602
TMEM120A	NCLN	ENSP00000473983	ENSP00000246117	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family	0.723
TMEM120A	ORMDL2	ENSP00000473983	ENSP00000243045	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	ORM1-like protein 2; Negative regulator of sphingolipid synthesis	0.671
TMEM120A	PPAPDC3	ENSP00000473983	ENSP00000361338	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity)	0.700
TMEM120A	TM7SF2	ENSP00000473983	ENSP00000279263	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Delta(14)-sterol reductase; Involved in the conversion of lanosterol to cholesterol	0.587
TMEM120A	TMEM115	ENSP00000473983	ENSP00000266025	Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family	Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi; Rhomboid family	0.583

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