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  • 11.0 [archived version]
STRINGSTRING
GOLGA1 GOLGA1 UBALD2 UBALD2 NPEPPS NPEPPS GUSB GUSB ENSG00000269590 ENSG00000269590 GLA GLA MGAM MGAM NAGA NAGA ENGASE ENGASE SULT1C3 SULT1C3 TCN1 TCN1
"ENSG00000269590" - Uncharacterized protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSG00000269590Uncharacterized protein (195 aa)    
Predicted Functional Partners:
SULT1C3
Sulfotransferase 1C3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor and has low sulphotransferase activity towards various substrates with alcohol groups (in vitro). May catalyze the sulfate conjugation of xenobiotic compounds and endogenous substrates; Sulfotransferases, cytosolic (304 aa)
      
   
  0.541
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family (651 aa)
      
   
  0.530
TCN1
Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach; Belongs to the eukaryotic cobalamin transport proteins family (433 aa)
            
  0.526
GLA
Galactosidase alpha; Belongs to the glycosyl hydrolase 27 family (429 aa)
      
 
  0.503
NPEPPS
Puromycin-sensitive aminopeptidase; Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain; Aminopeptidases (919 aa)
      
   
  0.455
NAGA
Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (411 aa)
      
 
  0.441
MGAM
Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing (1857 aa)
      
   
  0.438
GOLGA1
Golgin subfamily A member 1; Probably involved in maintaining Golgi structure (767 aa)
            
  0.414
ENGASE
Cytosolic endo-beta-N-acetylglucosaminidase; Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N’-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol (743 aa)
            
  0.412
UBALD2
UBA-like domain-containing protein 2; UBA like domain containing 2; Belongs to the UBALD family (164 aa)
            
  0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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