TEX101 protein (human) - STRING database

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TEX101

Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing (267 aa)

Predicted Functional Partners:

LY6K

0.974

SPACA4

0.968

LYPD3

0.960

GPIHBP1

0.952

LYPD4

0.949

VNN2

0.936

LYPD5

0.932

LYPD2

0.927

LY6H

0.924

LY6G6C

0.924

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPIHBP1	LY6G6C	ENSP00000480053	ENSP00000364978	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	0.916
GPIHBP1	LY6H	ENSP00000480053	ENSP00000399485	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Lymphocyte antigen 6H; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3-beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons; LY6/PLAUR domain containing	0.979
GPIHBP1	LY6K	ENSP00000480053	ENSP00000292430	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Lymphocyte antigen 6K; Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth; LY6/PLAUR domain containing	0.958
GPIHBP1	LYPD2	ENSP00000480053	ENSP00000352163	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	LY6/PLAUR domain containing 2	0.939
GPIHBP1	LYPD3	ENSP00000480053	ENSP00000244333	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing	0.952
GPIHBP1	LYPD4	ENSP00000480053	ENSP00000476510	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	LY6/PLAUR domain containing 4	0.918
GPIHBP1	LYPD5	ENSP00000480053	ENSP00000367185	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	LY6/PLAUR domain containing 5	0.932
GPIHBP1	SPACA4	ENSP00000480053	ENSP00000312774	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	0.926
GPIHBP1	TEX101	ENSP00000480053	ENSP00000472308	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing	0.952
GPIHBP1	VNN2	ENSP00000480053	ENSP00000322276	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Vanins	0.902
LY6G6C	GPIHBP1	ENSP00000364978	ENSP00000480053	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing	0.916
LY6G6C	LY6H	ENSP00000364978	ENSP00000399485	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Lymphocyte antigen 6H; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3-beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons; LY6/PLAUR domain containing	0.942
LY6G6C	LY6K	ENSP00000364978	ENSP00000292430	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Lymphocyte antigen 6K; Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth; LY6/PLAUR domain containing	0.937
LY6G6C	LYPD2	ENSP00000364978	ENSP00000352163	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	LY6/PLAUR domain containing 2	0.931
LY6G6C	LYPD3	ENSP00000364978	ENSP00000244333	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing	0.927
LY6G6C	LYPD4	ENSP00000364978	ENSP00000476510	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	LY6/PLAUR domain containing 4	0.931
LY6G6C	LYPD5	ENSP00000364978	ENSP00000367185	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	LY6/PLAUR domain containing 5	0.936
LY6G6C	SPACA4	ENSP00000364978	ENSP00000312774	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	0.943
LY6G6C	TEX101	ENSP00000364978	ENSP00000472308	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing	0.924
LY6G6C	VNN2	ENSP00000364978	ENSP00000322276	Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing	Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Vanins	0.900

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