TMEM185A protein (human) - STRING database

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TMEM185A

Transmembrane protein 185A; Belongs to the TMEM185 family (350 aa)

Predicted Functional Partners:

AFF2

0.804

FRA10AC1

0.725

FMR1

0.711

GPR137C

0.610

GPR157

0.557

CSNK1G1

0.548

TMEM181

0.533

BGN

0.527

PAQR5

0.493

GPR137B

0.488

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFF2	FMR1	ENSP00000359489	ENSP00000359506	AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family	Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...]	0.846
AFF2	FRA10AC1	ENSP00000359489	ENSP00000360488	AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family	Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex	0.720
AFF2	TMEM185A	ENSP00000359489	ENSP00000471932	AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family	Transmembrane protein 185A; Belongs to the TMEM185 family	0.804
BGN	TMEM185A	ENSP00000327336	ENSP00000471932	Biglycan; May be involved in collagen fiber assembly; Small leucine rich repeat proteoglycans	Transmembrane protein 185A; Belongs to the TMEM185 family	0.527
CSNK1G1	TMEM185A	ENSP00000305777	ENSP00000471932	Casein kinase I isoform gamma-1; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN	Transmembrane protein 185A; Belongs to the TMEM185 family	0.548
FMR1	AFF2	ENSP00000359506	ENSP00000359489	Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...]	AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family	0.846
FMR1	FRA10AC1	ENSP00000359506	ENSP00000360488	Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...]	Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex	0.560
FMR1	TMEM185A	ENSP00000359506	ENSP00000471932	Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...]	Transmembrane protein 185A; Belongs to the TMEM185 family	0.711
FRA10AC1	AFF2	ENSP00000360488	ENSP00000359489	Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex	AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family	0.720
FRA10AC1	FMR1	ENSP00000360488	ENSP00000359506	Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex	Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...]	0.560
FRA10AC1	TMEM185A	ENSP00000360488	ENSP00000471932	Protein FRA10AC1; FRA10A associated CGG repeat 1; Spliceosomal C complex	Transmembrane protein 185A; Belongs to the TMEM185 family	0.725
GPR137B	GPR157	ENSP00000355551	ENSP00000366628	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.503
GPR137B	PAQR5	ENSP00000355551	ENSP00000378803	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	Membrane progestin receptor gamma; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation; Progestin and adipoQ receptor family	0.440
GPR137B	TMEM181	ENSP00000355551	ENSP00000356057	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication	0.476
GPR137B	TMEM185A	ENSP00000355551	ENSP00000471932	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	Transmembrane protein 185A; Belongs to the TMEM185 family	0.488
GPR137C	GPR157	ENSP00000315106	ENSP00000366628	Integral membrane protein GPR137C; G protein-coupled receptor 137C	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.766
GPR137C	PAQR5	ENSP00000315106	ENSP00000378803	Integral membrane protein GPR137C; G protein-coupled receptor 137C	Membrane progestin receptor gamma; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation; Progestin and adipoQ receptor family	0.606
GPR137C	TMEM181	ENSP00000315106	ENSP00000356057	Integral membrane protein GPR137C; G protein-coupled receptor 137C	Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication	0.619
GPR137C	TMEM185A	ENSP00000315106	ENSP00000471932	Integral membrane protein GPR137C; G protein-coupled receptor 137C	Transmembrane protein 185A; Belongs to the TMEM185 family	0.610
GPR157	GPR137B	ENSP00000366628	ENSP00000355551	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	0.503

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