• Version:
  • 11.0 [archived version]
STRINGSTRING
ALDH16A1 ALDH16A1 PRR19 PRR19 DDX27 DDX27 NGRN NGRN ZNF480 ZNF480 TRIM28 TRIM28 FBXW12 FBXW12 ALS2CL ALS2CL
"ZNF480" - Zinc finger protein 480 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF480Zinc finger protein 480; Involved in transcriptional regulation as an activator; Zinc fingers C2H2-type (535 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.910
PRR19
Proline-rich protein 19; Proline rich 19 (356 aa)
           
  0.571
ALS2CL
ALS2 C-terminal-like protein; Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics; VPS9 domain containing (953 aa)
           
  0.474
FBXW12
F-box/WD repeat-containing protein 12; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and WD repeat domain containing (464 aa)
           
  0.420
ALDH16A1
Aldehyde dehydrogenase 16 family member A1 (802 aa)
       
 
  0.415
DDX27
Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3’ end formation of ribosomal 47S rRNA; DEAD-box helicases (796 aa)
       
 
  0.403
NGRN
Neugrin; May be involved in neuronal differentiation (291 aa)
           
  0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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