node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASB7 | DEFB115 | ENSP00000328327 | ENSP00000383398 | Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family | Beta-defensin 115; Has antibacterial activity; Defensins, beta | 0.532 |
ASB7 | FAM135A | ENSP00000328327 | ENSP00000410768 | Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | 0.440 |
ASB7 | ZNF726 | ENSP00000328327 | ENSP00000471516 | Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.672 |
DEFB115 | ASB7 | ENSP00000383398 | ENSP00000328327 | Beta-defensin 115; Has antibacterial activity; Defensins, beta | Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family | 0.532 |
DEFB115 | FAM135A | ENSP00000383398 | ENSP00000410768 | Beta-defensin 115; Has antibacterial activity; Defensins, beta | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | 0.556 |
DEFB115 | MTRNR2L12 | ENSP00000383398 | ENSP00000468991 | Beta-defensin 115; Has antibacterial activity; Defensins, beta | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | 0.447 |
DEFB115 | PARD6G | ENSP00000383398 | ENSP00000343144 | Beta-defensin 115; Has antibacterial activity; Defensins, beta | Partitioning defective 6 homolog gamma; Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity); PDZ domain containing | 0.429 |
DEFB115 | ZNF726 | ENSP00000383398 | ENSP00000471516 | Beta-defensin 115; Has antibacterial activity; Defensins, beta | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.709 |
DNAJB11 | ZNF726 | ENSP00000414398 | ENSP00000471516 | DnaJ homolog subfamily B member 11; Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity; DNAJ heat shock proteins | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.450 |
FAM135A | ASB7 | ENSP00000410768 | ENSP00000328327 | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family | 0.440 |
FAM135A | DEFB115 | ENSP00000410768 | ENSP00000383398 | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | Beta-defensin 115; Has antibacterial activity; Defensins, beta | 0.556 |
FAM135A | MTRNR2L12 | ENSP00000410768 | ENSP00000468991 | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | 0.581 |
FAM135A | PRR32 | ENSP00000410768 | ENSP00000360166 | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | Proline-rich protein 32; Proline rich 32 | 0.520 |
FAM135A | ZNF726 | ENSP00000410768 | ENSP00000471516 | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.668 |
MTRNR2L12 | DEFB115 | ENSP00000468991 | ENSP00000383398 | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | Beta-defensin 115; Has antibacterial activity; Defensins, beta | 0.447 |
MTRNR2L12 | FAM135A | ENSP00000468991 | ENSP00000410768 | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | Protein FAM135A; Family with sequence similarity 135 member A; Belongs to the FAM135 family | 0.581 |
MTRNR2L12 | PARD6G | ENSP00000468991 | ENSP00000343144 | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | Partitioning defective 6 homolog gamma; Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity); PDZ domain containing | 0.472 |
MTRNR2L12 | PRR32 | ENSP00000468991 | ENSP00000360166 | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | Proline-rich protein 32; Proline rich 32 | 0.651 |
MTRNR2L12 | ZNF726 | ENSP00000468991 | ENSP00000471516 | Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor; Belongs to the humanin family | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.559 |
MYOT | ZNF726 | ENSP00000239926 | ENSP00000471516 | Myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells; I-set domain containing | Zinc finger protein 726; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.426 |