node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKDD1B | ANKRA2 | ENSP00000471417 | ENSP00000296785 | Ankyrin repeat and death domain containing 1B | Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity); Ankyrin repeat domain containing | 0.427 |
ANKDD1B | ANKRD22 | ENSP00000471417 | ENSP00000360998 | Ankyrin repeat and death domain containing 1B | Ankyrin repeat domain-containing protein 22; Ankyrin repeat domain containing | 0.410 |
ANKDD1B | CAPN8 | ENSP00000471417 | ENSP00000355837 | Ankyrin repeat and death domain containing 1B | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | 0.445 |
ANKDD1B | CCDC135 | ENSP00000471417 | ENSP00000353942 | Ankyrin repeat and death domain containing 1B | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.407 |
ANKDD1B | FHL3 | ENSP00000471417 | ENSP00000362107 | Ankyrin repeat and death domain containing 1B | Four and a half LIM domains 3 | 0.520 |
ANKDD1B | SH3BP2 | ENSP00000471417 | ENSP00000422168 | Ankyrin repeat and death domain containing 1B | SH3 domain-binding protein 2; Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism; Pleckstrin homology domain containing | 0.412 |
ANKDD1B | TAGAP | ENSP00000471417 | ENSP00000356033 | Ankyrin repeat and death domain containing 1B | T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation | 0.435 |
ANKRA2 | ANKDD1B | ENSP00000296785 | ENSP00000471417 | Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity); Ankyrin repeat domain containing | Ankyrin repeat and death domain containing 1B | 0.427 |
ANKRD22 | ANKDD1B | ENSP00000360998 | ENSP00000471417 | Ankyrin repeat domain-containing protein 22; Ankyrin repeat domain containing | Ankyrin repeat and death domain containing 1B | 0.410 |
CAPN8 | ANKDD1B | ENSP00000355837 | ENSP00000471417 | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | Ankyrin repeat and death domain containing 1B | 0.445 |
CAPN8 | CCDC135 | ENSP00000355837 | ENSP00000353942 | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.580 |
CAPN8 | FHL3 | ENSP00000355837 | ENSP00000362107 | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | Four and a half LIM domains 3 | 0.422 |
CAPN8 | TAGAP | ENSP00000355837 | ENSP00000356033 | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation | 0.528 |
CCDC135 | ANKDD1B | ENSP00000353942 | ENSP00000471417 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Ankyrin repeat and death domain containing 1B | 0.407 |
CCDC135 | CAPN8 | ENSP00000353942 | ENSP00000355837 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | 0.580 |
CCDC135 | FHL3 | ENSP00000353942 | ENSP00000362107 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Four and a half LIM domains 3 | 0.621 |
CCDC135 | TAGAP | ENSP00000353942 | ENSP00000356033 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation | 0.688 |
FHL3 | ANKDD1B | ENSP00000362107 | ENSP00000471417 | Four and a half LIM domains 3 | Ankyrin repeat and death domain containing 1B | 0.520 |
FHL3 | CAPN8 | ENSP00000362107 | ENSP00000355837 | Four and a half LIM domains 3 | Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family | 0.422 |
FHL3 | CCDC135 | ENSP00000362107 | ENSP00000353942 | Four and a half LIM domains 3 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.621 |