• Version:
  • 11.0 [archived version]
STRINGSTRING
SH3BP2 SH3BP2 ANKRD22 ANKRD22 ANKDD1B ANKDD1B ANKRA2 ANKRA2 CAPN8 CAPN8 FHL3 FHL3 TAGAP TAGAP CCDC135 CCDC135
"ANKDD1B" - Ankyrin repeat and death domain containing 1B in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
ANKDD1BAnkyrin repeat and death domain containing 1B (528 aa)    
Predicted Functional Partners:
FHL3
Four and a half LIM domains 3 (280 aa)
       
 
  0.520
CAPN8
Calpain-8; Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity); Belongs to the peptidase C2 family (703 aa)
       
 
  0.445
TAGAP
T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation (731 aa)
     
   
  0.435
ANKRA2
Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity); Ankyrin repeat domain containing (313 aa)
   
   
  0.427
SH3BP2
SH3 domain-binding protein 2; Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism; Pleckstrin homology domain containing (618 aa)
       
      0.412
ANKRD22
Ankyrin repeat domain-containing protein 22; Ankyrin repeat domain containing (191 aa)
   
   
  0.410
CCDC135
Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family (874 aa)
     
   
  0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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