• Version:
  • 11.0 [archived version]
STRINGSTRING
C20orf195 C20orf195 OR2Z1 OR2Z1 MBD3L1 MBD3L1 C11orf70 C11orf70 UBL4B UBL4B ZNF558 ZNF558 TRIM61 TRIM61 TRIM28 TRIM28 RCBTB2 RCBTB2 ZZZ3 ZZZ3 ZBTB21 ZBTB21
"ZNF558" - Zinc finger protein 558 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF558Zinc finger protein 558; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (402 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
OR2Z1
Olfactory receptor 2Z1; Odorant receptor; Olfactory receptors, family 2 (314 aa)
           
  0.699
TRIM61
Putative tripartite motif-containing protein 61; Tripartite motif containing 61; Ring finger proteins (209 aa)
     
 
  0.605
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
     
   
  0.542
UBL4B
Ubiquitin-like protein 4B; Ubiquitin like 4B (174 aa)
     
 
  0.541
ZBTB21
Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor; BTB domain containing (1066 aa)
           
  0.531
MBD3L1
Methyl-CpG-binding domain protein 3-like 1; Transcriptional repressor (194 aa)
       
 
  0.530
RCBTB2
RCC1 and BTB domain containing protein 2 (556 aa)
     
      0.520
C20orf195
Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195 (318 aa)
           
  0.494
C11orf70
Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70 (267 aa)
           
  0.493
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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