ZNF616 protein (human) - STRING database

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ZNF616

Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type (781 aa)

Predicted Functional Partners:

TRIM28

0.928

OR5I1

0.582

C11orf24

0.528

SH3RF2

0.514

DPY19L1

0.509

SYNDIG1

0.484

CCDC115

0.473

PTPN20A

0.445

BTBD3

0.442

CDC14B

0.441

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTBD3	ZNF616	ENSP00000384545	ENSP00000471000	BTB/POZ domain-containing protein 3; Acts as a key regulator of dendritic field orientation during development of sensory cortex. Also directs dendrites toward active axon terminals when ectopically expressed (By similarity); BTB domain containing	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.442
C11orf24	CCDC115	ENSP00000307264	ENSP00000259229	Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	0.652
C11orf24	CDC14B	ENSP00000307264	ENSP00000364389	Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24	Dual specificity protein phosphatase CDC14B; Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint- following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases; Belongs to the protein-tyrosine ph [...]	0.484
C11orf24	ZNF616	ENSP00000307264	ENSP00000471000	Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.528
CCDC115	C11orf24	ENSP00000259229	ENSP00000307264	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24	0.652
CCDC115	ZNF616	ENSP00000259229	ENSP00000471000	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.473
CDC14B	C11orf24	ENSP00000364389	ENSP00000307264	Dual specificity protein phosphatase CDC14B; Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint- following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases; Belongs to the protein-tyrosine ph [...]	Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24	0.484
CDC14B	ZNF616	ENSP00000364389	ENSP00000471000	Dual specificity protein phosphatase CDC14B; Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint- following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases; Belongs to the protein-tyrosine ph [...]	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.441
DPY19L1	OR5I1	ENSP00000308695	ENSP00000301532	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	0.610
DPY19L1	SH3RF2	ENSP00000308695	ENSP00000424497	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family	0.571
DPY19L1	SYNDIG1	ENSP00000308695	ENSP00000366058	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	Synapse differentiation-inducing gene protein 1; May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation; Belongs to the CD225/Dispanin family	0.546
DPY19L1	ZNF616	ENSP00000308695	ENSP00000471000	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.509
OR5I1	DPY19L1	ENSP00000301532	ENSP00000308695	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	0.610
OR5I1	SH3RF2	ENSP00000301532	ENSP00000424497	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family	0.619
OR5I1	SYNDIG1	ENSP00000301532	ENSP00000366058	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	Synapse differentiation-inducing gene protein 1; May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation; Belongs to the CD225/Dispanin family	0.603
OR5I1	ZNF616	ENSP00000301532	ENSP00000471000	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.582
PTPN20A	ZNF616	ENSP00000363459	ENSP00000471000	Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates	Zinc finger protein 616; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.445
SH3RF2	DPY19L1	ENSP00000424497	ENSP00000308695	Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family	Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins	0.571
SH3RF2	OR5I1	ENSP00000424497	ENSP00000301532	Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family	Olfactory receptor 5I1; Odorant receptor; Olfactory receptors, family 5	0.619
SH3RF2	SYNDIG1	ENSP00000424497	ENSP00000366058	Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family	Synapse differentiation-inducing gene protein 1; May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation; Belongs to the CD225/Dispanin family	0.545

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