TMEM59L protein (human) - STRING database

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TMEM59L

Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (342 aa)

Predicted Functional Partners:

FAM171B

0.839

TMEM179

0.640

TMEM177

0.628

TMEM178A

0.623

TUSC5

0.601

SCGN

0.587

FAM131B

0.571

TMEM88B

0.562

KBTBD11

0.561

TMEM130

0.558

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM131B	FAM171B	ENSP00000410603	ENSP00000304108	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	0.588
FAM131B	TMEM130	ENSP00000410603	ENSP00000413163	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Transmembrane protein 130	0.593
FAM131B	TMEM178A	ENSP00000410603	ENSP00000281961	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family	0.583
FAM131B	TMEM179	ENSP00000410603	ENSP00000450958	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Transmembrane protein 179; Belongs to the TMEM179 family	0.647
FAM131B	TMEM59L	ENSP00000410603	ENSP00000470879	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.571
FAM131B	TMEM88B	ENSP00000410603	ENSP00000455099	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	Transmembrane protein 88B	0.611
FAM171B	FAM131B	ENSP00000304108	ENSP00000410603	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	0.588
FAM171B	TMEM130	ENSP00000304108	ENSP00000413163	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 130	0.674
FAM171B	TMEM178A	ENSP00000304108	ENSP00000281961	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family	0.620
FAM171B	TMEM179	ENSP00000304108	ENSP00000450958	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 179; Belongs to the TMEM179 family	0.642
FAM171B	TMEM59L	ENSP00000304108	ENSP00000470879	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.839
FAM171B	TMEM88B	ENSP00000304108	ENSP00000455099	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	Transmembrane protein 88B	0.631
KBTBD11	TMEM59L	ENSP00000321544	ENSP00000470879	Kelch repeat and BTB domain containing 11	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.561
SCGN	TMEM59L	ENSP00000367197	ENSP00000470879	Secretagogin, EF-hand calcium binding protein; EF-hand domain containing	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.587
TMEM130	FAM131B	ENSP00000413163	ENSP00000410603	Transmembrane protein 130	Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family	0.593
TMEM130	FAM171B	ENSP00000413163	ENSP00000304108	Transmembrane protein 130	Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family	0.674
TMEM130	TMEM178A	ENSP00000413163	ENSP00000281961	Transmembrane protein 130	Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family	0.621
TMEM130	TMEM179	ENSP00000413163	ENSP00000450958	Transmembrane protein 130	Transmembrane protein 179; Belongs to the TMEM179 family	0.641
TMEM130	TMEM59L	ENSP00000413163	ENSP00000470879	Transmembrane protein 130	Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding	0.558
TMEM130	TMEM88B	ENSP00000413163	ENSP00000455099	Transmembrane protein 130	Transmembrane protein 88B	0.621

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