ENSG00000268083 protein (human)

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ENSG00000268083

Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (321 aa)

Predicted Functional Partners:

UBE2I

0.735

SCP2

0.705

ECI2

0.564

ACAT2

0.534

ACAT1

0.534

MED16

0.524

MOV10

0.521

ACSL1

0.505

RNASEH2B

0.504

ACADVL

0.487

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADVL	ACSL1	ENSP00000438689	ENSP00000422607	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	0.630
ACADVL	ECI2	ENSP00000438689	ENSP00000369461	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	0.659
ACADVL	ENSG00000268083	ENSP00000438689	ENSP00000470059	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	0.487
ACAT1	ACAT2	ENSP00000265838	ENSP00000356015	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2	0.947
ACAT1	ECI2	ENSP00000265838	ENSP00000369461	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	0.624
ACAT1	ENSG00000268083	ENSP00000265838	ENSP00000470059	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	0.534
ACAT1	SCP2	ENSP00000265838	ENSP00000360569	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	Non-specific lipid-transfer protein; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	0.588
ACAT2	ACAT1	ENSP00000356015	ENSP00000265838	Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	0.947
ACAT2	ECI2	ENSP00000356015	ENSP00000369461	Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	0.626
ACAT2	ENSG00000268083	ENSP00000356015	ENSP00000470059	Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2	Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	0.534
ACSL1	ACADVL	ENSP00000422607	ENSP00000438689	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	0.630
ACSL1	ECI2	ENSP00000422607	ENSP00000369461	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	0.609
ACSL1	ENSG00000268083	ENSP00000422607	ENSP00000470059	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	0.505
ACSL1	SCP2	ENSP00000422607	ENSP00000360569	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	Non-specific lipid-transfer protein; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	0.623
ECI2	ACADVL	ENSP00000369461	ENSP00000438689	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons; Belongs to the acyl-CoA dehydrogenase family	0.659
ECI2	ACAT1	ENSP00000369461	ENSP00000265838	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Acetyl-CoA acetyltransferase, mitochondrial; Plays a major role in ketone body metabolism	0.624
ECI2	ACAT2	ENSP00000369461	ENSP00000356015	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase 2	0.626
ECI2	ACSL1	ENSP00000369461	ENSP00000422607	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Long-chain-fatty-acid--CoA ligase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate; Acyl-CoA synthetase family	0.609
ECI2	ENSG00000268083	ENSP00000369461	ENSP00000470059	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Uncharacterized protein; Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	0.564
ECI2	SCP2	ENSP00000369461	ENSP00000360569	Enoyl-CoA delta isomerase 2, mitochondrial; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity)	Non-specific lipid-transfer protein; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	0.944

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