| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD55 | ZNF626 | ENSP00000342295 | ENSP00000469958 | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.520 |
| CNTNAP3B | ZNF626 | ENSP00000478671 | ENSP00000469958 | Contactin-associated protein-like 3B; Contactin associated protein like 3B | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.416 |
| DYNLT3 | ZNF626 | ENSP00000367841 | ENSP00000469958 | Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity); Belongs to the dynein light chain Tctex-type family | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.495 |
| GOLGA8J | ZNF626 | ENSP00000456401 | ENSP00000469958 | Golgin A8 family member J; Belongs to the GOLGA8 family | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.588 |
| MRI1 | ZNF626 | ENSP00000040663 | ENSP00000469958 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.471 |
| NME4 | ZNF626 | ENSP00000219479 | ENSP00000469958 | Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma- phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis. Binds to anionic phospholipids, predominantly to cardiolipin; the binding inhibits its phosphotransfer activity. Acts as mitochondria-specific NDK; its association with cardiol [...] | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.485 |
| PTGR1 | ZNF626 | ENSP00000385763 | ENSP00000469958 | Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.456 |
| RPL39L | ZNF626 | ENSP00000296277 | ENSP00000469958 | Ribosomal protein L39 like; Belongs to the eukaryotic ribosomal protein eL39 family | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.426 |
| TRIM28 | ZNF626 | ENSP00000253024 | ENSP00000469958 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.912 |
| TRMT10A | ZNF626 | ENSP00000273962 | ENSP00000469958 | tRNA methyltransferase 10 homolog A; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)- methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)- methyladenine at position 9 (m1A9) in tRNAs; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.412 |
| ZNF626 | ANKRD55 | ENSP00000469958 | ENSP00000342295 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing | 0.520 |
| ZNF626 | CNTNAP3B | ENSP00000469958 | ENSP00000478671 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Contactin-associated protein-like 3B; Contactin associated protein like 3B | 0.416 |
| ZNF626 | DYNLT3 | ENSP00000469958 | ENSP00000367841 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity); Belongs to the dynein light chain Tctex-type family | 0.495 |
| ZNF626 | GOLGA8J | ENSP00000469958 | ENSP00000456401 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Golgin A8 family member J; Belongs to the GOLGA8 family | 0.588 |
| ZNF626 | MRI1 | ENSP00000469958 | ENSP00000040663 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover | 0.471 |
| ZNF626 | NME4 | ENSP00000469958 | ENSP00000219479 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma- phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis. Binds to anionic phospholipids, predominantly to cardiolipin; the binding inhibits its phosphotransfer activity. Acts as mitochondria-specific NDK; its association with cardiol [...] | 0.485 |
| ZNF626 | PTGR1 | ENSP00000469958 | ENSP00000385763 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4 | 0.456 |
| ZNF626 | RPL39L | ENSP00000469958 | ENSP00000296277 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ribosomal protein L39 like; Belongs to the eukaryotic ribosomal protein eL39 family | 0.426 |
| ZNF626 | TRIM28 | ENSP00000469958 | ENSP00000253024 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.912 |
| ZNF626 | TRMT10A | ENSP00000469958 | ENSP00000273962 | Zinc finger protein 626; May be involved in transcriptional regulation; Zinc fingers C2H2-type | tRNA methyltransferase 10 homolog A; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)- methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)- methyladenine at position 9 (m1A9) in tRNAs; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family | 0.412 |
