SCGB2B2 protein (human) - STRING database

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SCGB2B2

Secretoglobin family 2B member 2; Secretoglobins (96 aa)

Predicted Functional Partners:

WTIP

0.566

SCGB2A2

0.558

ZNF599

0.555

ZNF30

0.539

BPIFA2

0.515

PAXBP1

0.497

UBA2

0.491

ZNF181

0.477

CYTH4

0.474

C22orf24

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPIFA2	SCGB2B2	ENSP00000253362	ENSP00000469876	BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa; Belongs to the BPI/LBP/Plunc superfamily. Plunc family	Secretoglobin family 2B member 2; Secretoglobins	0.515
C22orf24	SCGB2B2	ENSP00000248984	ENSP00000469876	Uncharacterized protein C22orf24; Chromosome 22 open reading frame 24	Secretoglobin family 2B member 2; Secretoglobins	0.473
CYTH4	SCGB2B2	ENSP00000248901	ENSP00000469876	Cytohesin-4; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP; Pleckstrin homology domain containing	Secretoglobin family 2B member 2; Secretoglobins	0.474
PAXBP1	SCGB2B2	ENSP00000328992	ENSP00000469876	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of ’Lys-4’ of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity)	Secretoglobin family 2B member 2; Secretoglobins	0.497
SCGB2A2	SCGB2B2	ENSP00000227918	ENSP00000469876	Mammaglobin-A; Secretoglobin family 2A member 2; Secretoglobins	Secretoglobin family 2B member 2; Secretoglobins	0.558
SCGB2B2	BPIFA2	ENSP00000469876	ENSP00000253362	Secretoglobin family 2B member 2; Secretoglobins	BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa; Belongs to the BPI/LBP/Plunc superfamily. Plunc family	0.515
SCGB2B2	C22orf24	ENSP00000469876	ENSP00000248984	Secretoglobin family 2B member 2; Secretoglobins	Uncharacterized protein C22orf24; Chromosome 22 open reading frame 24	0.473
SCGB2B2	CYTH4	ENSP00000469876	ENSP00000248901	Secretoglobin family 2B member 2; Secretoglobins	Cytohesin-4; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP; Pleckstrin homology domain containing	0.474
SCGB2B2	PAXBP1	ENSP00000469876	ENSP00000328992	Secretoglobin family 2B member 2; Secretoglobins	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of ’Lys-4’ of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity)	0.497
SCGB2B2	SCGB2A2	ENSP00000469876	ENSP00000227918	Secretoglobin family 2B member 2; Secretoglobins	Mammaglobin-A; Secretoglobin family 2A member 2; Secretoglobins	0.558
SCGB2B2	UBA2	ENSP00000469876	ENSP00000246548	Secretoglobin family 2B member 2; Secretoglobins	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	0.491
SCGB2B2	WTIP	ENSP00000469876	ENSP00000466953	Secretoglobin family 2B member 2; Secretoglobins	Wilms tumor protein 1-interacting protein; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadheri [...]	0.566
SCGB2B2	ZNF181	ENSP00000469876	ENSP00000420727	Secretoglobin family 2B member 2; Secretoglobins	Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.477
SCGB2B2	ZNF30	ENSP00000469876	ENSP00000403441	Secretoglobin family 2B member 2; Secretoglobins	Zinc finger protein 30; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.539
SCGB2B2	ZNF599	ENSP00000469876	ENSP00000333802	Secretoglobin family 2B member 2; Secretoglobins	Zinc finger protein 599; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.555
UBA2	SCGB2B2	ENSP00000246548	ENSP00000469876	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	Secretoglobin family 2B member 2; Secretoglobins	0.491
UBA2	WTIP	ENSP00000246548	ENSP00000466953	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	Wilms tumor protein 1-interacting protein; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadheri [...]	0.707
UBA2	ZNF181	ENSP00000246548	ENSP00000420727	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.431
UBA2	ZNF30	ENSP00000246548	ENSP00000403441	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	Zinc finger protein 30; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.467
UBA2	ZNF599	ENSP00000246548	ENSP00000333802	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes	Zinc finger protein 599; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.491

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